OCULAR MELANOMA
Clinical trials for OCULAR MELANOMA explained in plain language.
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New drug combo aims to tackle Hard-to-Treat cancers
Disease control TerminatedThis study tests a combination of two drugs, neratinib and valproate, in people with advanced solid tumors that have not responded to standard treatments. The first part finds the safest dose, and the second part focuses on cancers with a RAS mutation, like certain colon and panc…
Matched conditions: OCULAR MELANOMA
Phase: PHASE1, PHASE2 • Sponsor: Virginia Commonwealth University • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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New drug cocktail targets rare eye cancer
Disease control OngoingThis phase II trial tests two drugs—olaparib and pembrolizumab—together in 12 people with advanced uveal melanoma, a rare eye cancer that has spread. The goal is to see if the combination can shrink tumors or slow the disease. The study is active but no longer recruiting, and res…
Matched conditions: OCULAR MELANOMA
Phase: PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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New pill shows promise in Hard-to-Treat eye cancer
Disease control OngoingThis phase 2 trial tests a new drug called roginolisib against standard treatments in 85 adults with advanced uveal melanoma, a rare eye cancer. The study aims to see if roginolisib helps people live longer and improves their quality of life. Participants are randomly assigned to…
Matched conditions: OCULAR MELANOMA
Phase: PHASE2 • Sponsor: iOnctura • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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Can less radiation treat eye cancer just as well?
Knowledge-focused OngoingThis study tracks 42 people with ocular melanoma who received radiation therapy via eye plaque brachytherapy. Researchers want to see if using lower radiation doses can still keep the cancer from coming back while reducing harmful side effects. The goal is to find the safest effe…
Matched conditions: OCULAR MELANOMA
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC