New drug shows promise in fighting rare eye cancer

NCT ID NCT06717126

First seen Jan 17, 2026 · Last updated May 23, 2026 · Updated 17 times

Summary

This study tests a new drug called roginolisib in adults with advanced uveal melanoma, a rare eye cancer that has spread. About 85 participants will receive either roginolisib or standard treatment to see if the drug helps them live longer and improves their quality of life. The goal is to find a better option for people whose cancer has worsened after initial immunotherapy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • A.O.U.S. Santa Maria delle Scotte

    Siena, 53100, Italy

  • Beatson West of Scotland Cancer Centre, Glasgow (NHS Greater Glasgow & Clyde)

    Glasgow, G12 0YN, United Kingdom

  • Complejo Hospitalario Universitario de Santiago - CHUS

    Santiago de Compostela, 15706, Spain

  • Consorcio Hospital General Universitario de València - CHGUV

    Valencia, 46014, Spain

  • East and North Hertfordshire NHS Trust (Mount Vernon Cancer Centre)

    Northwood, Middlesex, HA6 2RN, United Kingdom

  • Hospital Universitario La Paz

    Madrid, 28046, Spain

  • Hospital Universitario Virgen Macarena, University of Seville

    Seville, Spain

  • IRCCS Istituto Clinico Humanitas

    Rozzano, 20089, Italy

  • IRCSS Istituto Oncologico Veneto UOS Oncologia 2 del Melanoma Ospedale Busonera

    Padova, 35128, Italy

  • IRCSS National Cancer Institute, "G.Pascale" Foundation Dip. CORP-S di Ricerca ed Assistenziale Cute, Melanoma lmmunologia Oncologica Sperimentale e Terapie Innovative

    Naples, 80131, Italy

  • Institut Catala d'Oncologia - ICO L'Hospitalet

    Barcelona, 08908, Spain

  • Royal Marsden Hospital

    London, SW3 6JJ, United Kingdom

  • SSD Tumori Rari e Melanoma Viale Orazio Flacco

    Bari, 70124, Italy

  • The Clatterbridge Cancer Centre NHS Foundation Trust

    Bebington, Wirral, CH63 4JH, United Kingdom

  • University College London Hospital NHS

    London, NW1 2PG, United Kingdom

  • University Hospital Southampton NHS Foundation

    Southampton, SO16 6YD, United Kingdom

Conditions

Explore the condition pages connected to this study.