OCULAR MELANOMA
Clinical trials for OCULAR MELANOMA explained in plain language.
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Can a vaccine keep melanoma from coming back? large trial tests immune boosters
Disease control CompletedThis phase 3 trial tested whether a yeast-derived immune stimulant (GM-CSF) and a peptide vaccine, alone or together, could prevent melanoma from returning after surgery. 815 patients with no visible cancer after complete surgical removal of advanced melanoma were randomly assign…
Matched conditions: OCULAR MELANOMA
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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New drug shows promise in shrinking eye cancer before surgery
Disease control CompletedThis phase 2 trial tested the drug darovasertib in 15 people with high-risk uveal melanoma (a rare eye cancer) who were scheduled for eye removal surgery. Participants took the drug for up to 4 weeks before surgery, and some continued for 6 months afterward. The main goals were t…
Matched conditions: OCULAR MELANOMA
Phase: PHASE2 • Sponsor: St Vincent's Hospital, Sydney • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Supercharged immune cells take on tough melanoma
Disease control CompletedThis early-phase trial tested a new personalized therapy called TBio-4101 for people with advanced melanoma that had stopped responding to standard treatments. The therapy uses a patient's own tumor-fighting immune cells, which are collected, multiplied in the lab, and then infus…
Matched conditions: OCULAR MELANOMA
Phase: PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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New combo therapy shows promise for brain metastases
Disease control CompletedThis early study tested combining the immunotherapy drug pembrolizumab with precise radiation (stereotactic radiosurgery) in 25 people with melanoma or lung cancer that had spread to the brain. The main goal was to check for serious side effects. Researchers also tracked how long…
Matched conditions: OCULAR MELANOMA
Phase: PHASE1 • Sponsor: Emory University • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Scientists decode DNA of rare eye tumors to track Cancer's moves
Knowledge-focused CompletedThis study looked at the DNA changes (mutations) in eye cancers called ocular melanoma. Researchers analyzed tumor samples from 58 patients to understand how these cancers develop and spread. The goal was to identify key mutations that could lead to better treatments in the futur…
Matched conditions: OCULAR MELANOMA
Sponsor: The Wellcome Sanger Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC