NON-ALCOHOLIC STEATOHEPATITIS
Clinical trials for NON-ALCOHOLIC STEATOHEPATITIS explained in plain language.
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New hope for fatty liver: stomach procedure may beat diet alone
Disease control Recruiting nowThis study looks at whether a minimally invasive stomach-shrinking procedure (endoscopic sleeve gastroplasty) plus lifestyle changes is better than lifestyle changes alone for treating obesity and a serious liver condition called MASH. About 132 adults with a BMI of 30 or higher …
Matched conditions: NON-ALCOHOLIC STEATOHEPATITIS
Phase: NA • Sponsor: Pichamol Jirapinyo, MD, MPH • Aim: Disease control
Last updated Jun 15, 2026 18:54 UTC
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Can a diabetes drug tame fatty liver? new study investigates
Disease control Recruiting nowThis study looks at how the liver of people with non-alcoholic fatty liver disease (NAFLD) responds to eating, and whether the drug semaglutide can help. About 84 adults with NAFLD and healthy volunteers will take part. Participants will have liver tests, biopsies, and take weekl…
Matched conditions: NON-ALCOHOLIC STEATOHEPATITIS
Phase: PHASE2 • Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Disease control
Last updated Jun 01, 2026 17:54 UTC
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New combo test could spot liver damage before it's too late
Diagnosis Recruiting nowThis study looks at 1,200 adults referred for liver checks to see if combining blood markers, genetic data, and gut bacteria analysis can detect liver scarring earlier than current methods. The goal is to identify advanced liver disease in the community and reduce unnecessary spe…
Matched conditions: NON-ALCOHOLIC STEATOHEPATITIS
Sponsor: Manchester University NHS Foundation Trust • Aim: Diagnosis
Last updated Jun 16, 2026 21:35 UTC
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Needle-Free hope: new blood test may detect liver scarring without painful biopsy
Diagnosis Recruiting nowThis study is collecting blood samples from 575 adults with fatty liver disease to find new, noninvasive tests that can detect liver scarring (fibrosis). Currently, doctors rely on a painful liver biopsy to check for scarring, but this research aims to replace that with a simple …
Matched conditions: NON-ALCOHOLIC STEATOHEPATITIS
Sponsor: Roche Diagnostics GmbH • Aim: Diagnosis
Last updated Jun 15, 2026 18:56 UTC
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800 patients help scientists build liver disease models
Knowledge-focused Recruiting nowThis study collects tissue and blood samples from 800 people with chronic liver disease or liver cancer. Researchers will use these samples to create lab models, like cell clusters and mouse tumors, to test new treatments. The goal is to better understand these diseases and devel…
Matched conditions: NON-ALCOHOLIC STEATOHEPATITIS
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 16, 2026 21:36 UTC
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Healthy volunteers needed to test safety of experimental NASH drug
Knowledge-focused Recruiting nowThis early-stage study tests an experimental drug called HEC169584 in 96 healthy adults aged 18 to 45. The main goal is to check if the drug is safe and how the body processes it, not to treat any disease. Results will help guide future studies for non-alcoholic steatohepatitis (…
Matched conditions: NON-ALCOHOLIC STEATOHEPATITIS
Phase: PHASE1 • Sponsor: Sunshine Lake Pharma Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 16, 2026 21:36 UTC
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New ultrasound technique could improve liver scar detection in obese patients
Knowledge-focused Recruiting nowThis study looks at whether a special ultrasound done during an endoscopy (EUS-SWE) can better detect liver scarring in people with fatty liver disease and a high BMI. Standard non-invasive tests are often less accurate in this group. The study will enroll 150 adults who are alre…
Matched conditions: NON-ALCOHOLIC STEATOHEPATITIS
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 16, 2026 21:33 UTC
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Mini-livers reveal secrets of fatty liver disease gene
Knowledge-focused Recruiting nowThis study uses tiny, lab-grown liver models (organoids) made from patient cells to understand how a specific gene variant (I148M of PNPLA3) contributes to non-alcoholic steatohepatitis (NASH), a serious fatty liver disease. Researchers will expose these mini-livers to fatty acid…
Matched conditions: NON-ALCOHOLIC STEATOHEPATITIS
Phase: NA • Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:54 UTC
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New study seeks to uncover why some liver patients develop cancer
Knowledge-focused Recruiting nowThis study aims to find out why some people with fatty liver disease or alcohol-related liver disease develop liver cancer. Researchers will look at metabolic factors, immune system responses, and imaging data from 710 participants. The goal is to identify early warning signs, es…
Matched conditions: NON-ALCOHOLIC STEATOHEPATITIS
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:53 UTC
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Mayo clinic launches major study to uncover hidden fatty liver cases
Knowledge-focused Recruiting nowThis study aims to find out how many people have non-alcoholic fatty liver disease (NAFLD) and its more serious form, NASH, without knowing it. Researchers will use advanced MRI scans to diagnose the condition in 800 adults from Olmsted County, Minnesota. Participants will be fol…
Matched conditions: NON-ALCOHOLIC STEATOHEPATITIS
Phase: NA • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:05 UTC