NASH
Clinical trials for NASH explained in plain language.
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New drug shows promise against fatty liver in early trial
Disease control CompletedThis study tested a new medicine called DD01 in 67 overweight or obese adults with a type of fatty liver disease (MASLD/MASH). The goal was to see if DD01 could reduce liver fat by at least 30% over 48 weeks compared to a placebo. The trial also checked safety and other liver hea…
Matched conditions: NASH
Phase: PHASE2 • Sponsor: Neuraly, Inc. • Aim: Disease control
Last updated May 17, 2026 02:55 UTC
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Plant power: phytosterol supplement shows promise for fatty liver
Disease control CompletedThis study looked at whether taking a natural plant supplement called phytosterol can help people with nonalcoholic fatty liver disease (NAFLD). 27 adults took the supplement for 3 months. Researchers measured changes in liver enzymes, cholesterol, insulin, and inflammation. The …
Matched conditions: NASH
Phase: NA • Sponsor: University of Jordan • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New drug shows promise for fatty liver in early trial
Disease control CompletedThis study tested a drug called elobixibat in 47 adults with nonalcoholic fatty liver disease (NAFLD) or its more serious form, NASH. The goal was to see if the drug could lower bad cholesterol (LDL-C) compared to a placebo over 16 weeks. The trial also checked for side effects. …
Matched conditions: NASH
Phase: PHASE2 • Sponsor: Albireo • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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Blood tests may replace painful liver biopsies for diabetes patients
Knowledge-focused CompletedThis study looked at whether two blood tests, eLIFT and FibroMeter, can accurately detect advanced liver fibrosis (scarring) in people with type 2 diabetes. The researchers compared these blood tests to a specialized ultrasound (FibroScan) and, in some cases, liver biopsy. The go…
Matched conditions: NASH
Phase: NA • Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 02:57 UTC
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Liver disease and COVID shots: new study checks immune response
Knowledge-focused CompletedThis completed study looked at how people with chronic liver disease (like hepatitis B, C, or fatty liver) respond to COVID-19 vaccines. Researchers measured antibody levels and tracked COVID-19 infections over 6 months in 233 adults. The goal was to see if liver disease severity…
Matched conditions: NASH
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated May 17, 2026 02:57 UTC
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Can a phone app help NASH patients get fit?
Knowledge-focused CompletedThis study tested whether a mobile health exercise program, called EL-FIT, is practical and safe for people with NASH (a type of fatty liver disease). Seventeen adults with NASH used the app to follow exercise sessions at home. The main goal was to see if at least half of them co…
Matched conditions: NASH
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 12, 2026 13:43 UTC