NASAL POLYPS
Clinical trials for NASAL POLYPS explained in plain language.
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New injection could shrink nasal polyps without surgery
Disease control CompletedThis phase 3 trial tested a biologic drug called depemokimab in 276 adults with chronic sinusitis and nasal polyps. Participants received either the drug or a placebo as an injection under the skin. The study measured changes in polyp size and nasal blockage over 52 weeks to see …
Matched conditions: NASAL POLYPS
Phase: PHASE3 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Radical sinus surgery may beat standard for tough nasal polyps
Disease control CompletedThis study compared two types of sinus surgery for people with chronic sinusitis and nasal polyps that involve a type of inflammation called eosinophilic. One surgery (MRESS) removes more tissue, including the middle turbinate, while the standard surgery (FESS) preserves it. The …
Matched conditions: NASAL POLYPS
Phase: NA • Sponsor: Zheng Liu • Aim: Disease control
Last updated Jun 26, 2026 16:46 UTC
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New shot could shrink nasal polyps without surgery
Disease control CompletedThis Phase 3 trial tested a biologic drug called depemokimab in 264 adults with chronic sinusitis and nasal polyps. Participants received either the drug or a placebo as a shot under the skin. The study measured changes in polyp size and nasal blockage over 52 weeks. The goal is …
Matched conditions: NASAL POLYPS
Phase: PHASE3 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated Jun 26, 2026 14:58 UTC
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Asthma Drug's hidden effects revealed in small study
Knowledge-focused CompletedThis study looked at how mepolizumab, a biologic drug, changes inflammation in people with severe eosinophilic asthma. Researchers measured immune and metabolic markers in the nose, lungs, and blood of 15 adults. The goal was to better understand the drug's full impact beyond jus…
Matched conditions: NASAL POLYPS
Sponsor: Istituti Clinici Scientifici Maugeri SpA • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Scientists probe immune Molecule's role in stuffy nose disease
Knowledge-focused CompletedThis study looked at how a molecule called IL-5 affects different cells in the sinuses of people with nasal polyps and a related condition called aspirin-exacerbated respiratory disease. Researchers analyzed tissue samples from 30 participants to understand how IL-5 contributes t…
Matched conditions: NASAL POLYPS
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC