MYELODYSPLASTIC SYNDROME(MDS)
Clinical trials for MYELODYSPLASTIC SYNDROME(MDS) explained in plain language.
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New transplant cocktail aims to tame blood cancer without severe side effects
Disease control Recruiting nowThis early-stage trial is testing a new combination of chemotherapy drugs (thiotepa, busulfan, and fludarabine) followed by a stem cell transplant for people with certain blood cancers like leukemia and myelodysplastic syndrome. The goal is to see if this approach can reduce the …
Matched conditions: MYELODYSPLASTIC SYNDROME(MDS)
Phase: PHASE1 • Sponsor: Sawa Ito, MD • Aim: Disease control
Last updated Jul 02, 2026 07:00 UTC
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New cord blood treatment could transform transplants for bone marrow diseases
Disease control Recruiting nowThis study tests whether a new cord blood stem cell product, Omidubicel, can improve transplant outcomes for people with severe aplastic anemia or a related bone marrow disorder. Participants receive a combination of stem cells from a family member and specially processed cord bl…
Matched conditions: MYELODYSPLASTIC SYNDROME(MDS)
Phase: PHASE1, PHASE2 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Experimental combo targets Hard-to-Treat cancers
Disease control Recruiting nowThis early-phase study is testing two drugs together — alpelisib and pembrolizumab — in people with metastatic breast cancer or melanoma that has spread to the brain or other organs. The main goal is to find a safe dose and see what side effects occur. Up to 50 adults whose cance…
Matched conditions: MYELODYSPLASTIC SYNDROME(MDS)
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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New combo therapy targets leukemia stem cells in blood cancer trial
Disease control Recruiting nowThis early-phase trial tests a new drug called nadunolimab combined with standard treatments (azacitidine, with or without venetoclax) in 40 adults with high-risk myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). The goal is to see if the combination is safe and to …
Matched conditions: MYELODYSPLASTIC SYNDROME(MDS)
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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New drug CLN-049 aims to fight Hard-to-Treat blood cancers
Disease control Recruiting nowThis early-stage trial tests a new drug called CLN-049 in about 60 adults with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) that has come back or not responded to treatment. CLN-049 is designed to help the body's immune cells attack cancer cells. The main goals …
Matched conditions: MYELODYSPLASTIC SYNDROME(MDS)
Phase: PHASE1 • Sponsor: Cullinan Therapeutics Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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Could a pill replace shots for MDS? early trial begins
Disease control Recruiting nowThis early-stage trial is testing an oral form of the cancer drug azacitidine (called ASTX030) for people with myelodysplastic syndrome (MDS). The goal is to see if the pill version reaches similar levels in the blood as the standard injection. About 40 adults with MDS will take …
Matched conditions: MYELODYSPLASTIC SYNDROME(MDS)
Phase: PHASE1 • Sponsor: Taiho Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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New hope for fanconi anemia: safer stem cell transplant trial opens
Disease control Recruiting nowThis study tests a stem cell transplant approach for people with Fanconi Anemia who don't have a perfectly matched donor. The goal is to see if using lower doses of chemotherapy before the transplant can reduce serious side effects. About 70 participants will receive a transplant…
Matched conditions: MYELODYSPLASTIC SYNDROME(MDS)
Phase: PHASE2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC