MYELODYSPLASTIC SYNDROME (MDS)
Clinical trials for MYELODYSPLASTIC SYNDROME (MDS) explained in plain language.
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Researchers test if kidney health changes transplant drug dose for leukemia patients
Disease control Recruiting nowThis study aims to understand how kidney function and race/ethnicity affect how the body processes a drug called treosulfan, which is used to prepare patients for a stem cell transplant. The research involves 36 adults with acute myeloid leukemia or myelodysplastic syndrome who a…
Matched conditions: MYELODYSPLASTIC SYNDROME (MDS)
Phase: PHASE1 • Sponsor: medac GmbH • Aim: Disease control
Last updated Apr 01, 2026 20:26 UTC
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New hope for rare blood disorder: gentler transplant trial seeks to save lives
Disease control Recruiting nowThis study is testing a modified stem cell transplant procedure for patients with Fanconi anemia who have developed severe blood problems like bone marrow failure or leukemia. The goal is to see if using lower doses of certain chemotherapy drugs and removing another medication ca…
Matched conditions: MYELODYSPLASTIC SYNDROME (MDS)
Phase: PHASE2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Early trial aims to tame tough cancers with Two-Pronged attack
Disease control Recruiting nowThis early-stage study is testing the safety and best dose of a two-drug combination (alpelisib and pembrolizumab) for patients with advanced breast cancer or melanoma that has spread. It aims to see if this combo can help control the disease, including in cases where cancer has …
Matched conditions: MYELODYSPLASTIC SYNDROME (MDS)
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New drug combo targets tough blood cancers
Disease control Recruiting nowThis study is testing a new drug, NADUNOLIMAB, in combination with standard treatments for two types of blood cancer: Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML). The main goals are to find a safe dose and see if this new combination can help control the disea…
Matched conditions: MYELODYSPLASTIC SYNDROME (MDS)
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 31, 2026 12:10 UTC
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Experimental drug aims to rally immune system against tough blood cancers
Disease control Recruiting nowThis is the first study in people of an experimental drug called CLN-049 for adults with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) that has returned or stopped responding to standard treatments. The main goals are to find a safe dose and see how the drug move…
Matched conditions: MYELODYSPLASTIC SYNDROME (MDS)
Phase: PHASE1 • Sponsor: Cullinan Therapeutics Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Testing a pill to replace injections for blood disorder treatment
Disease control Recruiting nowThis early-stage study is testing a new oral pill combination (ASTX030) for patients with myelodysplastic syndrome (MDS), a bone marrow disorder. The main goal is to find a pill dose that works as well as the current standard injection treatment. Researchers will enroll about 40 …
Matched conditions: MYELODYSPLASTIC SYNDROME (MDS)
Phase: PHASE1 • Sponsor: Taiho Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Mar 02, 2026 15:24 UTC
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New hope for bone marrow failure: supercharged cord blood cells aim to fix transplant delays
Disease control Recruiting nowThis study is testing a new method for umbilical cord blood transplants in people with severe aplastic anemia or myelodysplastic syndrome (MDS), which are serious bone marrow diseases. Researchers are using specially prepared, expanded cord blood cells to try to help the transpla…
Matched conditions: MYELODYSPLASTIC SYNDROME (MDS)
Phase: PHASE1, PHASE2 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated Mar 02, 2026 15:21 UTC
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Listening to patients: japan study seeks to understand life with blood disorder
Knowledge-focused Recruiting nowThis study aims to understand the daily experiences, quality of life, and unmet needs of people in Japan living with a low-risk form of myelodysplastic syndrome (a bone marrow disorder) or unexplained anemia. Researchers will survey and interview approximately 50 participants who…
Matched conditions: MYELODYSPLASTIC SYNDROME (MDS)
Sponsor: Bristol-Myers Squibb • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC