MYELODYSPLASTIC SYNDROME (MDS)
Clinical trials for MYELODYSPLASTIC SYNDROME (MDS) explained in plain language.
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One donor, two transplants: new hope for patients with blood cancer and kidney failure
Disease control CompletedThis study tested a combined bone marrow and kidney transplant from a partially matched family donor for 10 people with both a serious blood disorder and chronic kidney disease. The goal was to treat both conditions with one donor, potentially reducing the need for lifelong anti-…
Matched conditions: MYELODYSPLASTIC SYNDROME (MDS)
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 17, 2026 03:19 UTC
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Expanded cord blood cells show promise in speeding recovery for blood cancer patients
Disease control CompletedThis study tested a new cord blood product called NiCord, which is grown in a lab to have more stem cells, against standard cord blood transplants for people with blood cancers like leukemia and lymphoma. The goal was to see if NiCord helps the body rebuild its blood and immune s…
Matched conditions: MYELODYSPLASTIC SYNDROME (MDS)
Phase: PHASE3 • Sponsor: Gamida Cell ltd • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New drug combo shows promise for Hard-to-Treat blood cancers
Disease control CompletedThis early-stage study tested a new drug called PRT2527, alone or combined with other drugs (zanubrutinib or venetoclax), in 86 people with blood cancers that returned or didn't respond to standard treatments. The main goals were to find a safe dose and check for side effects. Re…
Matched conditions: MYELODYSPLASTIC SYNDROME (MDS)
Phase: PHASE1 • Sponsor: Prelude Therapeutics • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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New drug combo shows promise for rare blood cancers
Disease control CompletedThis study tested a new pill called pelabresib in people with certain blood cancers, including myelofibrosis and leukemia. The goal was to see if it could shrink enlarged spleens and reduce the need for blood transfusions. The drug was given alone or with another medicine (ruxoli…
Matched conditions: MYELODYSPLASTIC SYNDROME (MDS)
Phase: PHASE1, PHASE2 • Sponsor: Constellation Pharmaceuticals • Aim: Disease control
Last updated May 08, 2026 12:01 UTC
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Healthy volunteers test new MDS drug LP-001 for safety
Knowledge-focused CompletedThis early-stage study tested LP-001 in 68 healthy adults aged 18-50 to see if it is safe and how the body handles it. The drug is being developed for myelodysplastic syndrome (MDS), a blood disorder. The study gave single and multiple doses to gather key information before testi…
Matched conditions: MYELODYSPLASTIC SYNDROME (MDS)
Phase: PHASE1 • Sponsor: Longbio Pharma • Aim: Knowledge-focused
Last updated May 17, 2026 03:19 UTC