New drug CLN-049 aims to fight Hard-to-Treat blood cancers

NCT ID NCT05143996

Recruiting now Disease control Sponsor: Cullinan Therapeutics Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests a new drug called CLN-049 in about 60 adults with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) that has come back or not responded to treatment. CLN-049 is designed to help the body's immune cells attack cancer cells. The main goals are to check the drug's safety and how it moves through the body.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia myelodysplastic syndrome Myelodysplastic Syndromes

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MYELODYSPLASTIC SYNDROME (MDS) RELAPSED/REFRACTORY ACUTE MYELOID LEUKEMIA (AML)

Contacts and locations

Locations

Cincinnati Children's Hospital Medical Center
WITHDRAWN

Cincinnati, Ohio, 45229, United States
Duke Cancer Center
RECRUITING

Durham, North Carolina, 27710, United States
Emory University Hospital
RECRUITING

Atlanta, Georgia, 30322, United States
MD Anderson
RECRUITING

Houston, Texas, 77030, United States
Massachusetts General Hospital
COMPLETED

Boston, Massachusetts, 02114, United States
Moffitt Cancer Center
RECRUITING

Tampa, Florida, 33612, United States
New York University
RECRUITING

New York, New York, 10016, United States
Roswell Park Cancer Institute
RECRUITING

Buffalo, New York, 14263, United States
UCLA
RECRUITING

Los Angeles, California, 90095, United States
University of Alabama O'Neal Cancer Center
RECRUITING

Birmingham, Alabama, 35233, United States
University of Miami Health System
RECRUITING

Miami, Florida, 33136, United States

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