New Immune-Boosting drug targets Hard-to-Treat blood cancers
NCT ID NCT05143996
First seen Nov 26, 2025 · Last updated May 16, 2026 · Updated 20 times
Summary
This early-stage study tests a new drug called CLN-049 in about 60 adults whose acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) has come back or not responded to treatment. CLN-049 is designed to help the body's immune cells attack cancer cells. The main goals are to check the drug's safety and how it moves through the body.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cincinnati Children's Hospital Medical Center
WITHDRAWNCincinnati, Ohio, 45229, United States
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Duke Cancer Center
RECRUITINGDurham, North Carolina, 27710, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Emory University Hospital
RECRUITINGAtlanta, Georgia, 30322, United States
Contact Email: •••••@•••••
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MD Anderson
RECRUITINGHouston, Texas, 77030, United States
Contact Email: •••••@•••••
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Massachusetts General Hospital
COMPLETEDBoston, Massachusetts, 02114, United States
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
Contact Email: •••••@•••••
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New York University
RECRUITINGNew York, New York, 10016, United States
Contact
Contact Email: •••••@•••••
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Roswell Park Cancer Institute
RECRUITINGBuffalo, New York, 14263, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UCLA
RECRUITINGLos Angeles, California, 90095, United States
Contact Email: •••••@•••••
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University of Alabama O'Neal Cancer Center
RECRUITINGBirmingham, Alabama, 35233, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University of Miami Health System
RECRUITINGMiami, Florida, 33136, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Conditions
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