MUSCULOSKELETAL PAIN

This early-stage trial tests whether injecting a patient's own stem cells into the knee can safely treat osteoarthritis and cartilage defects. Sixteen adults with knee pain will receive one injection of stem cells grown from their own bone marrow. Researchers will track side effe…

This study tests whether a postbiotic supplement called resO can help adults aged 18-75 with joint discomfort, stiffness, or reduced mobility. Forty participants will take either resO or a placebo for 4 weeks, and researchers will measure changes in physical function, pain, and a…

This study compares two short-term pain relief methods for acute musculoskeletal injuries: a steroid dose pack (methylprednisolone) versus a combination of acetaminophen (Tylenol) and ibuprofen (Motrin). Sixty adults with new injuries (less than 2 weeks old) will take one of the …

This study looks at whether a digital health program (Hinge Health) plus a wearable pain relief device (Enso) can help people with chronic low back pain feel better and move more easily. About 196 adults with back pain for at least 3 months will be randomly assigned to either the…

This study compares personalized electro-acupuncture and auricular-acupuncture against usual care for treating chronic pain in adults with musculoskeletal pain or fibromyalgia. Participants are split into three groups: two receive different acupuncture methods, and one receives s…

This study looks at whether osteopathic manipulation, a type of hands-on treatment, can help adults aged 40 and older who have both pain and thinking problems like trouble with memory or focus. The researchers will measure changes in pain, thinking skills, and stress-related mark…

This study looks at whether coaching existing workplace health and safety committees can improve employee health, safety, and well-being. About 3,300 healthcare workers in New England will take part. Researchers will compare coached teams to uncoached ones to see if team engageme…

This study follows 1,500 people with long-term pain who are joining rehabilitation programs. Researchers want to understand how insomnia symptoms influence pain, function, and work ability. The goal is to use this knowledge to improve future treatments for chronic pain.

This study looks at how fear of movement (kinesiophobia), pain level, and physical abilities are connected in older adults with muscle or joint pain. Researchers will measure balance, strength, and fear in 60 people aged 65 and older during a single 30-minute session. The goal is…

This study uses artificial intelligence to analyze video recordings of surgeons during operations, identifying risky postures that can lead to muscle and joint pain. Researchers will then give surgeons a short educational session and video feedback to see if it helps them move mo…

This study follows 275 teens aged 11–18 with chronic muscle or joint pain to find biological and behavioral markers that predict recovery versus ongoing pain. Researchers measure pain intensity and how much pain limits daily activities. The goal is to better understand why some t…