MULTIPLE SCLEROSIS (MS) PRIMARY PROGRESSIVE
Clinical trials for MULTIPLE SCLEROSIS (MS) PRIMARY PROGRESSIVE explained in plain language.
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New oral drug could slow MS progression in major trial
Disease control Recruiting nowThis phase 3 trial tests whether the oral drug orelabrutinib can slow disability progression in people with primary progressive multiple sclerosis (PPMS). About 705 adults aged 18–60 with PPMS will receive either orelabrutinib or a placebo for up to 5 years. The study measures ti…
Matched conditions: MULTIPLE SCLEROSIS (MS) PRIMARY PROGRESSIVE
Phase: PHASE3 • Sponsor: Zenas BioPharma (USA), LLC • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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CAR t therapy takes on lupus, MS, and more in first human safety trial
Disease control Recruiting nowThis early-stage study tests a new treatment called HBI0101 CAR T for people with severe autoimmune diseases like lupus, multiple sclerosis, and rheumatoid arthritis that haven't improved with standard treatments. The main goal is to find a safe dose and check for side effects in…
Matched conditions: MULTIPLE SCLEROSIS (MS) PRIMARY PROGRESSIVE
Phase: PHASE1 • Sponsor: Polina Stepensky • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Could donor cells stop MS progression? early trial launches
Disease control Recruiting nowThis early-stage trial tests a cell therapy called TRX319 in 39 adults with progressive multiple sclerosis (MS). The goal is to see if it is safe and to find the best dose. Participants receive TRX319 infusions, sometimes after a chemotherapy drug called bendamustine, and are fol…
Matched conditions: MULTIPLE SCLEROSIS (MS) PRIMARY PROGRESSIVE
Phase: PHASE1, PHASE2 • Sponsor: Tr1X, Inc. • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Can a home balance game boost brain and body in MS?
Symptom relief Recruiting nowThis study tests a home-based balance training program for people with multiple sclerosis (MS). The program combines stepping games, strength, and thinking tasks. Researchers will compare it to a simple stretching routine in 75 adults with MS to see if it improves physical functi…
Matched conditions: MULTIPLE SCLEROSIS (MS) PRIMARY PROGRESSIVE
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Your Phone's selfie camera could be the new MS monitor
Knowledge-focused Recruiting nowThis study looks at whether short selfie videos taken on a phone can accurately measure walking and speech changes in people with multiple sclerosis (MS). About 300 adults with MS will record 5 videos every 3 months for a year and also attend some in-person visits. The goal is to…
Matched conditions: MULTIPLE SCLEROSIS (MS) PRIMARY PROGRESSIVE
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC