MICROBIAL COLONIZATION

This study tests whether adding extra protein to breast milk during the first two weeks of life helps extremely preterm infants (born at 28 weeks or earlier) gain more lean body mass and develop a healthier gut microbiome. About 150 babies will be randomly assigned to receive eit…

This study compares banked donor breast milk to preterm formula for late preterm infants (born at 34–36 weeks) who need extra nutrition while their mothers' milk supply increases. Researchers will track the babies' weight gain and analyze their gut bacteria to see which supplemen…

This study looks at whether cleaning the mouth of very premature infants every 3-4 hours can reduce harmful bacteria and lower the risk of pneumonia and other breathing problems. Researchers will follow 40 infants born before 32 weeks and weighing less than 1500 grams, comparing …

This study planned to test a treatment called MET-2, a mix of gut bacteria, to help clear antibiotic-resistant germs from the body after a bloodstream infection. It was designed for adults not in intensive care who had a resistant infection. The trial was withdrawn before enrolli…

This early study tests whether transferring a parent's healthy nasal bacteria to their newborn can help prevent staph infections. Researchers will give the baby a nasal spray containing the parent's bacteria or a placebo, then monitor the baby's nose bacteria and safety. The stud…

This study looks at how the bacteria in a pregnant woman's gut (her microbiome) and her nutrition affect her baby's growth and health. Researchers are following 800 young pregnant women (28 and under) in Toronto throughout pregnancy and for a year after birth. They collect stool,…

This study is collecting saliva, stool, blood, bile, and tumor samples from 200 people undergoing surgery for pancreatic or related cancers. Researchers want to see if the types of bacteria in these samples can help predict who will have complications after surgery and how the ca…

This study looks at how eating a diet rich in pulses—like beans, lentils, and peas—affects the gut microbiome, feelings of fullness, and appetite hormones. Researchers are enrolling 44 overweight or obese adults who will follow a high-pulse diet for four weeks. The goal is to see…

This study looks at how introducing solid foods like sweet potato or pear changes the gut bacteria of breastfed babies. Researchers will track 102 infants and their mothers to see how these first foods affect digestion, health, and early brain development. The goal is to learn ho…