MICROBIAL COLONIZATION

This study looks at whether giving extra protein in breast milk to extremely premature babies (born at 28 weeks or earlier) during their first two weeks of life helps them gain more lean muscle and develop a healthier mix of gut bacteria. About 150 infants will take part. The goa…

This study planned to test a treatment called MET-2, a mix of gut bacteria, to help clear antibiotic-resistant germs from the body after a bloodstream infection. It was designed for adults not in intensive care who had a resistant infection. The trial was withdrawn before enrolli…

This early-stage study tests whether transferring a parent's healthy nasal bacteria to their newborn can help prevent the baby from carrying staph germs. The trial involves 34 infants in the NICU and their parents. Researchers will check if the baby's nose bacteria become more di…

This study looks at how eating pulses like beans and lentils changes the bacteria in your gut and affects your appetite. Researchers will measure gut microbes, appetite hormones, and other health markers in 44 overweight adults. Participants will eat a special diet and provide bl…

This study looks at how the bacteria in a pregnant woman's gut (her microbiome) and her nutrition affect her baby's growth and health. Researchers are following 800 young pregnant women (28 and under) in Toronto throughout pregnancy and for a year after birth. They collect stool,…

This study aims to understand how the bacteria living in your body (the microbiome) influence recovery after surgery for pancreatic or related cancers. Researchers will collect saliva, blood, stool, and tumor samples from 200 adult patients before and after surgery. The goal is t…

This study looks at whether cleaning the mouths of very premature babies more often (every 3-4 hours vs. every 12 hours) can reduce harmful bacteria and lower the risk of serious lung problems like pneumonia. Researchers will follow 150 babies born before 32 weeks and weighing le…

This study looks at how the food babies eat changes the bacteria in their gut and how that relates to their growth and development. About 100 healthy breastfed infants, ages 4 to 7.5 months, will be observed as they start solid foods like sweet potato or pear. The goal is to unde…