METASTATIC HER2-NEGATIVE BREAST CARCINOMA
Clinical trials for METASTATIC HER2-NEGATIVE BREAST CARCINOMA explained in plain language.
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Custom-Made vaccine targets tough cancers in early trial
⭐️ VACCINE ⭐️ Recruiting nowThis early-phase study is testing a personalized vaccine made from each patient's unique tumor mutations. The goal is to see if it is safe and can help the immune system fight advanced breast cancer, melanoma, and non-small cell lung cancer. About 25 adults whose cancers have spr…
Matched conditions: METASTATIC HER2-NEGATIVE BREAST CARCINOMA
Phase: PHASE1 • Sponsor: Fred Hutchinson Cancer Center • Aim: ⭐️ VACCINE ⭐️
Last updated May 11, 2026 20:52 UTC
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New vaccine combo aims to control advanced breast cancer
Disease control Recruiting nowThis study tests a vaccine called STEMVAC alongside standard hormone therapy or chemotherapy for people with hormone receptor-positive, HER2-negative breast cancer that has spread. The vaccine is designed to train the immune system to attack cancer cells. The trial will check saf…
Matched conditions: METASTATIC HER2-NEGATIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: University of Washington • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Smart dosing trial aims to tame metastatic breast cancer
Disease control Recruiting nowThis study tests a new way of giving the chemotherapy drug capecitabine to people with metastatic ER+ breast cancer. Instead of a fixed dose, the dose is adjusted based on how the tumor responds on scans and blood tests. The goal is to control the cancer for as long as possible w…
Matched conditions: METASTATIC HER2-NEGATIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 11, 2026 20:40 UTC
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Can a PET scan predict breast cancer drug success?
Knowledge-focused Recruiting nowThis study tests whether a special PET scan can predict if a drug combination (abemaciclib plus hormone therapy) will work for people with advanced hormone receptor-positive, HER2-negative breast cancer. About 60 participants will get the treatment and have imaging scans to see i…
Matched conditions: METASTATIC HER2-NEGATIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: University of Washington • Aim: Knowledge-focused
Last updated May 17, 2026 02:19 UTC
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Gene-Guided cancer therapy: a new hope for advanced tumors?
Knowledge-focused Recruiting nowThis study screens patients with advanced solid tumors to find genetic changes in their cancer cells. Based on those results, patients may be matched to a treatment trial that targets their specific tumor mutations. The goal is to improve how doctors choose combination therapies …
Matched conditions: METASTATIC HER2-NEGATIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC