METASTATIC COLORECTAL CANCER (CRC)
Clinical trials for METASTATIC COLORECTAL CANCER (CRC) explained in plain language.
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Custom immune cells take on advanced colorectal cancer in new trial
Disease control Recruiting nowThis early-stage trial is testing a personalized T-cell therapy called iNeo-Vac-T01 for people with advanced colorectal cancer that has not responded to standard treatments. The therapy is custom-made for each patient based on the unique markers (neoantigens) in their tumor. The …
Matched conditions: METASTATIC COLORECTAL CANCER (CRC)
Phase: PHASE1 • Sponsor: Ying Yuan, MD • Aim: Disease control
Last updated May 17, 2026 00:29 UTC
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New hope for colorectal cancer: experimental drug combo enters final trial phase
Disease control Recruiting nowThis study tests whether a new drug called ivonescimab, combined with standard chemotherapy, works better than the current standard treatment (bevacizumab plus chemo) for people with metastatic colorectal cancer that has spread. About 600 adults who have not had prior treatment f…
Matched conditions: METASTATIC COLORECTAL CANCER (CRC)
Phase: PHASE3 • Sponsor: Summit Therapeutics • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New chemo cocktail aims to outperform standard treatment for advanced colon cancer
Disease control Recruiting nowThis study tests whether a new chemotherapy combination (NALIRIFOX) plus targeted therapy works better than the standard treatment (FOLFOX) plus targeted therapy for people with metastatic colorectal cancer that cannot be removed by surgery. About 144 adults who have not had prio…
Matched conditions: METASTATIC COLORECTAL CANCER (CRC)
Phase: PHASE3 • Sponsor: Shanghai Zhongshan Hospital • Aim: Disease control
Last updated May 11, 2026 20:40 UTC
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New hope for advanced colon cancer: drug combo trial launches
Disease control Recruiting nowThis study tests a new combination of chemotherapy (5FU-based) plus the targeted drug fruquintinib as the very first treatment for people with advanced colorectal cancer that cannot be removed by surgery or has spread. About 50 participants will receive the treatment in cycles, a…
Matched conditions: METASTATIC COLORECTAL CANCER (CRC)
Phase: PHASE2 • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated May 07, 2026 18:42 UTC
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New pill takes on hard-to-treat KRAS cancers in first human trial
Disease control Recruiting nowThis early-phase study tests a new drug called BBO-11818 in adults with advanced lung, pancreatic, or colorectal cancers that have a KRAS mutation. The main goals are to check safety and find the best dose, while also seeing if the drug can shrink tumors. About 387 participants w…
Matched conditions: METASTATIC COLORECTAL CANCER (CRC)
Phase: PHASE1 • Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) • Aim: Disease control
Last updated May 07, 2026 18:41 UTC
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CBD trial aims to shield cancer patients from Chemo's painful side effects
Prevention Recruiting nowThis early study is testing whether CBD supplements can prevent nerve damage caused by a common chemotherapy drug. Researchers will give CBD capsules to some colorectal cancer patients during their treatment to see if it protects their nerves. The study focuses on whether patient…
Matched conditions: METASTATIC COLORECTAL CANCER (CRC)
Phase: EARLY_PHASE1 • Sponsor: Fox Chase Cancer Center • Aim: Prevention
Last updated Apr 23, 2026 12:43 UTC
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Blood test may help choose best retreatment for colorectal cancer
Knowledge-focused Recruiting nowThis study looks at whether a simple blood test (ctDNA) can help doctors decide if it's safe and effective to retreat patients with metastatic colorectal cancer using a targeted therapy called anti-EGFR. Researchers will collect and analyze data from 250 patients who have already…
Matched conditions: METASTATIC COLORECTAL CANCER (CRC)
Sponsor: Niguarda Hospital • Aim: Knowledge-focused
Last updated May 04, 2026 16:29 UTC