Blood test may help decide who gets second chance at targeted cancer therapy
NCT ID NCT07536113
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This observational study looks at whether a liquid biopsy (ctDNA test) can help select metastatic colorectal cancer patients who might benefit from retreatment with anti-EGFR drugs. Researchers will collect data from 250 patients already screened in a prior trial. The goal is to see if ctDNA status predicts treatment success in a real-world setting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
anti-EGFR therapy (rechallenge)
What this could lead to
If successful, this study could show that ctDNA testing helps doctors decide which patients with metastatic colorectal cancer might benefit from retreatment with anti-EGFR drugs.
What could go wrong
This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may not apply to all patients, and the approach may not improve outcomes in practice.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for METASTATIC COLORECTAL CANCER (CRC) are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
ASST GOM Niguarda
RECRUITINGMilan, Italia, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••