METABOLIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS
Clinical trials for METABOLIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS explained in plain language.
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Could a weekly shot help more people donate part of their liver?
Disease control Not yet recruitingThis study tests whether a 12-week program combining a weekly injection of mazdutide (a drug that targets gut hormones) with lifestyle counseling can quickly reduce liver fat in overweight or obese people who want to donate part of their liver but are temporarily disqualified due…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS
Phase: PHASE2, PHASE3 • Sponsor: West China Hospital • Aim: Disease control
Last updated Jul 23, 2026 00:00 UTC
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New pill for fatty liver enters early human testing
Disease control Not yet recruitingThis early-stage study tests a new oral drug called ACT500 in 24 adults with fatty liver disease (MASLD). The main goal is to check safety and how the drug moves through the body. Participants take one pill daily in different dose groups. The study does not aim to cure the diseas…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS
Phase: PHASE1 • Sponsor: Xiamen Amoytop Biotech Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Can Weight-Loss surgery rewire the Liver's energy engine?
Knowledge-focused Not yet recruitingThis study looks at how bariatric surgery affects the liver's energy processing in people with obesity and fatty liver disease. Researchers will use safe, non-radioactive tracer infusions and MRI scans before, during, and six months after surgery to measure changes in liver metab…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Aug 14, 2026 00:00 UTC
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New MRI methods could spot liver damage earlier
Knowledge-focused Not yet recruitingThis study tests new MRI techniques to measure blood flow and tissue details in the liver. Researchers will scan 110 people, including healthy volunteers and those with chronic liver disease or fibrosis, to see if these scans can reliably detect liver damage. The goal is to devel…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS
Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jul 25, 2026 00:00 UTC
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Protein fingerprint may forecast liver cancer 15 years early
Knowledge-focused Not yet recruitingThis study looks at stored liver biopsy samples from 30 people with MASH (a fatty liver disease) to see if a protein test can predict who will develop liver cancer within 15 years. Half of the participants later got liver cancer, and half did not. Researchers will compare the pro…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Handheld scanner could make liver checks easier
Knowledge-focused Not yet recruitingThis study will compare a new handheld device to the standard iLivTouch system for measuring liver stiffness and fat in 224 adults with chronic liver disease. Participants will be tested with both devices while lying down and sitting. The goal is to see if the handheld device is …
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS
Sponsor: Hong You • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC