MALIGNANT GLIOMA
Clinical trials for MALIGNANT GLIOMA explained in plain language.
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New drug shows promise for kids with Hard-to-Treat cancers
Disease control CompletedThis study tested a drug called samotolisib in 18 children and teens whose cancers had spread, come back, or stopped responding to treatment. The drug works by blocking certain enzymes that cancer cells need to grow. The goal was to see if the drug could shrink or stop the cancer…
Matched conditions: MALIGNANT GLIOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Aggressive brain tumor trial combines three treatments to fight recurrence
Disease control CompletedThis study tested whether adding whole brain radiation and a drug called plerixafor to standard chemotherapy can help people with a newly diagnosed aggressive brain tumor (glioblastoma). Twenty-one adults took part. The goal was to see if the combination could delay tumor growth …
Matched conditions: MALIGNANT GLIOMA
Phase: PHASE2 • Sponsor: Lawrence D Recht • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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Experimental brain cancer therapy infused directly into tumors shows promise in early trial
Disease control CompletedThis early-phase study tested a new drug called D2C7-IT for people with recurrent malignant glioma, a serious brain cancer. The drug was delivered directly into the tumor through tiny tubes over 72 hours. The main goal was to find the safest dose and see if it could help control …
Matched conditions: MALIGNANT GLIOMA
Phase: PHASE1 • Sponsor: Darell Bigner • Aim: Disease control
Last updated May 13, 2026 16:01 UTC
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Blood tests may predict brain tumor treatment success
Knowledge-focused CompletedThis study looked at 47 adults with newly diagnosed glioblastoma or gliosarcoma to see if changes in immune cells in the blood could predict how well treatment works. Participants received a combination of immunotherapy drugs (ipilimumab and nivolumab) plus standard chemotherapy …
Matched conditions: MALIGNANT GLIOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC
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New brain scan may sharpen radiation targeting for glioma patients
Knowledge-focused CompletedThis study looked at whether a special PET scan (18F-DOPA) can better detect brain tumors in people with newly diagnosed gliomas who are about to start radiation therapy. Researchers compared results from standard scans and this PET scan to see if it helps plan more precise treat…
Matched conditions: MALIGNANT GLIOMA
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 11, 2026 20:53 UTC