MALIGNANT DIGESTIVE SYSTEM NEOPLASM

This study is testing whether a new, step-by-step dosing guide called the PAGODA algorithm can help prevent unplanned delays in FOLFOX chemotherapy for people with gastrointestinal cancers. About 420 participants will be randomly assigned to have their chemotherapy doses adjusted…

This study is testing a procedure to place a small tube (stent) in a blocked liver vein for patients with gastrointestinal cancers. The goal is to see if opening the vein is safe, helps keep it open, and improves patients' symptoms, nutrition, and overall well-being. Researchers …

This study is testing if giving a common chemotherapy drug (oxaliplatin) over 6 hours instead of the usual 2 hours can reduce or delay painful nerve damage in patients with gastrointestinal cancers. The goal is to help patients stay on their full, planned chemotherapy doses longe…

This study is testing whether a dietary supplement called fucoidan, derived from brown seaweed, can help prevent or reduce the severe fatigue that often comes with chemotherapy. It will involve 34 adults with gastrointestinal or gynecological cancers who are starting a specific t…

This study collects detailed information about side effects experienced by cancer patients receiving proton radiation therapy. Researchers will follow 5,000 patients to understand both short-term and long-term effects, aiming to predict risks and improve safety for future patient…

This study aims to discover what causes bile duct and gallbladder cancers and why treatments work differently for different people. Researchers will compare 1,500 participants, including cancer patients, healthy people, and people with liver disease. They will collect blood and t…

This study aims to understand how surgeons currently prevent dangerous blood clots in patients after major cancer surgery. It will survey and interview 500 surgeons and their teams across the U.S. to learn about their practices, identify barriers to following best-practice guidel…