LYMPHOBLASTIC LYMPHOMA

This study tests a vaccine designed to protect people who have had a stem cell transplant from a common virus called CMV. The virus can cause serious illness in those with weak immune systems. The vaccine uses a harmless virus to teach the body to fight CMV, aiming to reduce infe…

This study tests a vaccine called Triplex to prevent cytomegalovirus (CMV) infection in adults who have received a stem cell transplant. CMV can cause serious illness in people with weakened immune systems. The vaccine uses harmless pieces of CMV DNA to help the body build immuni…

This study tests whether adding levocarnitine, a natural nutrient, to standard chemotherapy can prevent severe liver damage in teens and young adults (ages 15-39) with leukemia or lymphoma. Liver toxicity from the chemotherapy drug asparaginase often forces treatment delays, whic…

This study tests a modified chemotherapy regimen (based on the BFM protocol) in 150 Chinese children and teens newly diagnosed with lymphoblastic lymphoma. The goal is to improve how long patients stay cancer-free compared to previous results. Participants receive intensive chemo…

This study tests a new form of chemotherapy called calaspargase pegol (SC-PEG) in 240 children and teens with acute lymphoblastic leukemia or lymphoblastic lymphoma. The goal is to see if giving it every 3 weeks is as safe and effective as the standard drug Oncaspar given every 2…

This study looks at whether training parents in specific skills can improve learning and school functioning for Latino children with acute leukemia or lymphoma. About 214 families will take part, with some parents receiving a high-intensity program and others getting standard sup…

This study collects bone marrow and blood samples, along with medical history, from people with multiple myeloma, Waldenstrom macroglobulinemia, and related disorders. The samples are stored in a tissue bank for future research to understand what causes these cancers and how to i…

This study tests whether a special website and video coaching for parents can help children aged 6-12 who were treated for leukemia or lymphoma improve their learning and school performance. Many children survive these cancers but may struggle with memory, attention, and thinking…