LUPUS NEPHRITIS (LN)
Clinical trials for LUPUS NEPHRITIS (LN) explained in plain language.
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Engineered immune cells take aim at Hard-to-Treat lupus
Disease control Not yet recruitingThis early-stage study tests a new treatment called C-CAR168 for people with lupus nephritis (kidney inflammation from lupus) that hasn't improved with standard therapies. The treatment uses a patient's own immune cells, modified to target and destroy harmful cells driving the di…
Matched conditions: LUPUS NEPHRITIS (LN)
Phase: PHASE1, PHASE2 • Sponsor: AbelZeta Inc. • Aim: Disease control
Last updated May 17, 2026 02:42 UTC
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Engineered immune cells take aim at lupus in new trial
Disease control Not yet recruitingThis early-stage trial tests a new treatment called BCMA-CD19-IL-15 cCAR T cells for people with severe lupus that hasn't responded to standard therapies. The treatment uses a patient's own immune cells, modified in a lab to target and destroy faulty immune cells that cause lupus…
Matched conditions: LUPUS NEPHRITIS (LN)
Phase: PHASE1, PHASE2 • Sponsor: iCell Gene Therapeutics • Aim: Disease control
Last updated May 17, 2026 02:40 UTC
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Could a single infusion of supercharged immune cells tame tough lupus?
Disease control Not yet recruitingThis early-stage trial tests a new treatment called CRC01 for people with severe lupus that has not responded to other therapies. CRC01 uses a patient's own immune cells, modified to target and calm the overactive immune system causing kidney damage. The study will check if the t…
Matched conditions: LUPUS NEPHRITIS (LN)
Phase: PHASE1, PHASE2 • Sponsor: Curocell Inc. • Aim: Disease control
Last updated May 12, 2026 13:41 UTC
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Could a common diabetes pill protect kidneys in lupus patients?
Disease control Not yet recruitingThis study tests whether dapagliflozin, a drug already used for diabetes and other kidney diseases, can help people with lupus nephritis—a serious kidney condition caused by lupus. About 33 adults with active lupus nephritis will receive either dapagliflozin or a placebo alongsid…
Matched conditions: LUPUS NEPHRITIS (LN)
Phase: PHASE4 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated May 11, 2026 20:48 UTC
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Engineered immune cells take on tough kidney diseases in first human test
Disease control Not yet recruitingThis early-stage study tests a new treatment for people with severe kidney diseases caused by the immune system attacking the kidneys (lupus nephritis, IgA nephropathy, or membranous nephropathy) that have not responded to standard therapies. The treatment uses specially engineer…
Matched conditions: LUPUS NEPHRITIS (LN)
Phase: EARLY_PHASE1 • Sponsor: Air Force Military Medical University, China • Aim: Disease control
Last updated May 04, 2026 16:23 UTC