LUPUS NEPHRITIS
Clinical trials for LUPUS NEPHRITIS explained in plain language.
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Personalized dosing may boost lupus kidney treatment success
Disease control Not yet recruitingThis study looks at whether regularly measuring the amount of mycophenolate mofetil (an immunosuppressant) in the blood can help more people with lupus-related kidney disease achieve kidney remission. About 100 adults with active lupus nephritis will be randomly assigned to eithe…
Matched conditions: LUPUS NEPHRITIS
Phase: NA • Sponsor: Federal University of Maranhao • Aim: Disease control
Last updated May 17, 2026 06:22 UTC
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New drug aims to tame lupus kidney disease in landmark trial
Disease control Not yet recruitingThis study tests a new medicine, SIM0278, in 60 adults with active lupus nephritis, a serious kidney complication of lupus. Participants will receive either SIM0278 or a placebo, along with standard therapy, to see if the drug helps improve kidney function over 52 weeks. The goal…
Matched conditions: LUPUS NEPHRITIS
Phase: PHASE2 • Sponsor: Simcere Pharmaceutical Co., Ltd • Aim: Disease control
Last updated May 17, 2026 06:15 UTC
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Could engineered immune cells tame tough lupus kidney disease?
Disease control Not yet recruitingThis study tests a new treatment called FT819 for people with moderate-to-severe lupus that affects the kidneys (lupus nephritis) and hasn't responded to other therapies. FT819 uses specially engineered immune cells from a donor to target and calm the overactive immune system. Th…
Matched conditions: LUPUS NEPHRITIS
Phase: PHASE2 • Sponsor: Fate Therapeutics • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Could a single infusion of supercharged immune cells tame tough lupus?
Disease control Not yet recruitingThis early-stage trial tests a new treatment called CRC01 for people with severe lupus that has not responded to other therapies. CRC01 uses a patient's own immune cells, modified to target and calm the overactive immune system causing kidney damage. The study will check if the t…
Matched conditions: LUPUS NEPHRITIS
Phase: PHASE1, PHASE2 • Sponsor: Curocell Inc. • Aim: Disease control
Last updated May 12, 2026 13:41 UTC
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Engineered immune cells take aim at Hard-to-Treat lupus kidney disease
Disease control Not yet recruitingThis early study tests a new treatment called CHT105 for people with lupus nephritis that hasn't responded to standard therapies. CHT105 uses specially engineered immune cells from healthy donors to target and destroy the faulty immune cells driving the disease. The main goals ar…
Matched conditions: LUPUS NEPHRITIS
Phase: NA • Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School • Aim: Disease control
Last updated Apr 29, 2026 15:01 UTC
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Zinc deficiency linked to kidney damage in lupus patients?
Knowledge-focused Not yet recruitingThis study will check if people with lupus nephritis (kidney inflammation caused by lupus) have low zinc levels. Researchers will measure zinc in the blood and see if it relates to kidney function tests like creatinine and eGFR. The goal is to understand the connection, not to te…
Matched conditions: LUPUS NEPHRITIS
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:03 UTC
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Blood test could replace painful kidney biopsies for lupus patients
Knowledge-focused Not yet recruitingThis study aims to find a better blood test to detect active kidney inflammation in people with lupus nephritis. Researchers will measure a specific antibody in the blood of 96 participants and compare it to results from kidney biopsies. The goal is to develop a less invasive way…
Matched conditions: LUPUS NEPHRITIS
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Apr 20, 2026 16:17 UTC