LUPUS ERYTHEMATOSUS, SYSTEMIC

This study tests a new drug, cenerimod, for adults with moderate-to-severe systemic lupus erythematosus (SLE). About 470 participants will receive either cenerimod or a placebo on top of their usual treatments for 12 months. The goal is to see if cenerimod can better control lupu…

This study tests a new drug called litifilimab for people with active systemic lupus erythematosus (SLE), a chronic autoimmune disease. About 548 adults already on standard lupus treatments will receive either litifilimab or a placebo as a shot every 4 weeks for a year. The goal …

This study follows 1620 lupus patients who are not responding well to current treatments to see how safe and effective Saphnelo (anifrolumab) is over the long term. Researchers will monitor for side effects like infections and allergic reactions. The goal is to gather real-world …

This study tests whether adding cenerimod to standard lupus treatments can better control moderate-to-severe symptoms. About 451 adults with lupus will receive either cenerimod or a placebo for 12 months. The goal is to see if cenerimod reduces disease activity without causing se…

This study tests a new drug called litifilimab for people with active systemic lupus erythematosus (SLE), a chronic autoimmune disease. About 562 adults already on standard lupus treatments will receive either high-dose, low-dose litifilimab, or a placebo as injections every 4 we…

This study looks at the long-term safety of cenerimod in adults with moderate-to-severe lupus. About 680 people who already completed a year-long study will take cenerimod for up to 3 more years, along with their usual lupus medications. Researchers will track side effects and se…

This study tests whether personalized coaching on physical activity and nutrition can reduce fatigue in people with lupus. 200 participants are split into two groups: one gets coaching on exercise and diet, the other gets standard lupus self-management education. The main goal is…

This study tests an online program designed to help people with inflammatory arthritis (like rheumatoid arthritis or lupus) keep their jobs. Participants get access to eLearning, an occupational therapist, and a vocational counselor. The goal is to see if the program improves wor…

This study looks at whether clinical pilates exercises can reduce fatigue, pain, and emotional distress in women with systemic lupus erythematosus (SLE). Researchers will measure changes in sleep, functional capacity, and quality of life in 30 women with low disease activity. The…

This study looks at immune cells (B cells) from people with autoimmune diseases like lupus, people with infections, and healthy volunteers. Researchers want to understand how these cells differ between groups. The goal is to learn more about the immune system, not to test a new t…

This study looks at how depression symptoms, like loss of interest, may make it harder for teens and young adults with lupus to keep up with their medical appointments. Researchers will test a mobile health app designed to improve both clinic engagement and depression. About 40 p…