LUPUS ERYTHEMATOSUS, SYSTEMIC

This study is collecting real-world information on the long-term safety and effectiveness of Saphnelo (anifrolumab) for people with systemic lupus erythematosus. It involves 1,620 patients who haven't responded well to current treatments. The goal is to monitor how the drug perfo…

This study aims to learn about the long-term safety and side effects of the drug cenerimod for adults with moderate-to-severe lupus. It will follow about 680 people who took part in earlier trials, giving them cenerimod along with their standard lupus medications for up to 3 year…

This study is testing an investigational drug called litifilimab for adults with active systemic lupus erythematosus (SLE). The goal is to see if adding monthly injections of litifilimab to a patient's standard lupus medications can better control the disease, reduce symptom flar…

This study is testing if a new oral drug called cenerimod helps control symptoms when added to standard treatments for adults with moderate-to-severe lupus. About 420 participants will take either cenerimod or a placebo pill daily for one year, while continuing their usual lupus …

This large, late-stage study is testing whether a new injectable drug called litifilimab can better control active systemic lupus. About 550 adults who are already on standard lupus medications will receive either the drug or a placebo for a year. The main goal is to see if litif…

This study is testing whether a drug called memantine can safely help with the memory and thinking problems (often called 'brain fog') that many people with lupus experience. For 14 weeks, 111 participants with lupus and measured cognitive impairment will receive either memantine…

This study is testing whether a specific exercise program, called clinical Pilates, can help women with lupus feel better. It aims to see if these exercises can reduce common problems like severe tiredness, pain, poor sleep, and low mood. The study will compare a home exercise pr…

This study aims to understand if depression makes it harder for teens and young adults with lupus to keep up with their medical care. Researchers are testing a specially designed mobile app to see if it's a helpful and practical tool for improving both mood and care engagement. T…

This research study aims to understand how autoimmune diseases like lupus develop by comparing immune cells from people with autoimmune conditions, people with infectious diseases, and healthy individuals. Researchers will collect blood and sometimes bone marrow samples from 2,50…