Lupus patients may soon ditch meds: CAR T-Cell trial offers hope
NCT ID NCT07015983
First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 32 times
Summary
This study tests a new treatment called CC-97540 for people with active lupus, including lupus nephritis, who haven't gotten better with standard medicines. The treatment uses specially engineered immune cells (CAR T cells) to target and destroy faulty immune cells causing the disease. The main goal is to see if participants can achieve remission without needing ongoing lupus medications.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Contact
Locations
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ASST Grande Ospedale Metropolitano Niguarda
RECRUITINGMilan, Milano, 20162, Italy
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Atlantic Health System Overlook Medical Center
RECRUITINGSummit, New Jersey, 07901, United States
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Baylor Scott and White Research Institute
RECRUITINGDallas, Texas, 75246, United States
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CHU Montpellier Lapeyronie Hospital
RECRUITINGMontpellier, Hérault, 34295, France
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Carolinas HealthCare System SouthPark
RECRUITINGCharlotte, North Carolina, 28211, United States
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Centre Hospitalier Universitaire de Rennes - Hôpital Pontchaillou
RECRUITINGRennes, 35033, France
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Centro Hospitalar Universitário Lisboa Norte, E.P.E. - Hospital de Santa Maria
RECRUITINGLisbon, Lisbon District, 1649-035, Portugal
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Charité - Universitaetsmedizin Berlin - Campus Bejnamin Franklin
RECRUITINGBerlin, 10117, Germany
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Chiba University Hospital
RECRUITINGChiba, 260-8677, Japan
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Cincinnati Children's Hospital Medical Center
RECRUITINGCincinnati, Ohio, 45229, United States
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
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Columbia University Irving Medical Center
RECRUITINGNew York, New York, 10032, United States
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Emory University School of Medicine
RECRUITINGAtlanta, Georgia, 30322, United States
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Florida Medical Clinic Orlando Health
RECRUITINGZephyrhills, Florida, 33542, United States
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore
RECRUITINGRome, Lazio, 00168, Italy
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H.R.U Málaga - Hospital General
RECRUITINGMálaga, 29011, Spain
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Hospital Clínico Universitario Virgen de la Arrixaca
RECRUITINGMurcia, 30120, Spain
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Hospital Italiano de Buenos Aires
RECRUITINGABB, Buenos Aires F.D., C1199ABB, Argentina
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Hospital Sant Joan de Déu
RECRUITINGEsplugues de Llobregat, Barcelona [Barcelona], 08950, Spain
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Hospital Universitari Vall d'Hebron
RECRUITINGBarcelona, Barcelona [Barcelona], 08035, Spain
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Hospital for Special Surgery
RECRUITINGNew York, New York, 10021, United States
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Icahn School of Medicine at Mount Sinai
RECRUITINGNew York, New York, 10029, United States
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Juntendo University Hospital
RECRUITINGBunkyo-ku, Tokyo, 113-8431, Japan
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Keio university hospital
RECRUITINGShinjuku-ku, Tokyo, 1608582, Japan
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King's College Hospital
RECRUITINGLondon, London, City of, SE5 9RL, United Kingdom
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Kyushu University Hospital
RECRUITINGFukuoka, 812-8582, Japan
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Local Institution - 0011
NOT_YET_RECRUITINGRochester, Minnesota, 55905, United States
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Local Institution - 0021
NOT_YET_RECRUITINGSão Paulo, São Paulo, 01409-001, Brazil
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Local Institution - 0022
NOT_YET_RECRUITINGSão Paulo, 05652-900, Brazil
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Local Institution - 0023
NOT_YET_RECRUITINGBuenos Aires, Buenos Aires F.D., C1118AAT, Argentina
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Local Institution - 0038
NOT_YET_RECRUITINGLos Angeles, California, 90027, United States
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Local Institution - 0042
NOT_YET_RECRUITINGJerusalem, 9112001, Israel
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Local Institution - 0044
NOT_YET_RECRUITINGRome, Roma, 00165, Italy
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Local Institution - 0045
NOT_YET_RECRUITINGToronto, Ontario, M5G 1X8, Canada
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Local Institution - 0047
NOT_YET_RECRUITINGCopenhagen, 2100, Denmark
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Local Institution - 0051
NOT_YET_RECRUITINGLos Angeles, California, 90095, United States
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Local Institution - 0055
NOT_YET_RECRUITINGSapporo, Hokkaido, 0608648, Japan
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Local Institution - 0058
NOT_YET_RECRUITINGSão Paulo, São Paulo, 01509-010, Brazil
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Local Institution - 0061
WITHDRAWNLondon, London, City of, NW1 2PG, United Kingdom
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Local Institution - 0070
NOT_YET_RECRUITINGPisa, Tuscany, 56126, Italy
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Local Institution - 0073
NOT_YET_RECRUITINGOrlando, Florida, 32803, United States
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Local Institution - 0076
NOT_YET_RECRUITINGAthens, Georgia, 30606, United States
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Local Institution - 0077
NOT_YET_RECRUITINGCórdoba, X5016, Argentina
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Local Institution - 0079
NOT_YET_RECRUITINGAtlanta, Georgia, 30322, United States
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Local Institution - 0081
NOT_YET_RECRUITINGToulouse, Haute-Garonne, 31059, France
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Local Institution - 0082
NOT_YET_RECRUITINGNew York, New York, 10016, United States
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Local Institution - 0083
NOT_YET_RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Local Institution - 0084
NOT_YET_RECRUITINGHerne, 44649, Germany
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Local Institution - 0086
NOT_YET_RECRUITINGBaton Rouge, Louisiana, 70836, United States
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Local Institution - 0087
NOT_YET_RECRUITINGMadrid, 28006, Spain
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Local Institution - 0088
NOT_YET_RECRUITINGDonostia / San Sebastian, Gipuzkoa, 20014, Spain
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Local Institution - 0090
NOT_YET_RECRUITINGMetropolitan Borough of Wirral, Merseyside, L63 4JY, United Kingdom
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Local Institution - 0091
NOT_YET_RECRUITINGLiverpool, L9 7AL, United Kingdom
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Local Institution - 0092
NOT_YET_RECRUITINGMemphis, Tennessee, 38120, United States
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Local Institution - 0093
NOT_YET_RECRUITINGNewport Beach, California, 92658, United States
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Local Institution - 0094
NOT_YET_RECRUITINGBoston, Massachusetts, 02114, United States
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Local Institution - 0095
NOT_YET_RECRUITINGNew York, New York, 10032, United States
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Local Institution - 0096
NOT_YET_RECRUITINGAnn Arbor, Michigan, 48109, United States
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Local Institution - 0098
NOT_YET_RECRUITINGDallas, Texas, 75390-9068, United States
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Local Institution - 0099
NOT_YET_RECRUITINGToronto, Ontario, M5T 2S8, Canada
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Local Institution - 0101
NOT_YET_RECRUITINGManhasset, New York, 11030, United States
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Local Institution - 0102
NOT_YET_RECRUITINGCrownhill, Plymouth, PL6 8DH, United Kingdom
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Local Institution - 0104
NOT_YET_RECRUITINGSan Antonio, Texas, 78229, United States
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Local Institution - 0105
NOT_YET_RECRUITINGDenver, Colorado, 80218, United States
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Local Institution - 0106
NOT_YET_RECRUITINGScottsdale, Arizona, 85259, United States
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Local Institution - 0107
NOT_YET_RECRUITINGBuenos Aires, B1629ODT, Argentina
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Local Institution - 0108
NOT_YET_RECRUITINGIndianapolis, Indiana, 46250, United States
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Local Institution - 0109
NOT_YET_RECRUITINGStrasbourg, 67098, France
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Lucile Packard Children's Hospital
RECRUITINGPalo Alto, California, 94304, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mayo Clinic in Florida
RECRUITINGJacksonville, Florida, 32224, United States
Contact Phone: •••-•••-••••
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Medizinische Universität Wien
RECRUITINGVienna, State of Vienna, 1090, Austria
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
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Narodowy Instytut Onkologii - Oddzial w Gliwicach
RECRUITINGGliwice, Silesian Voivodeship, 44-101, Poland
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Odense Universitetshospital
RECRUITINGOdense, Region Syddanmark, 5000, Denmark
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Okayama University Hospital
RECRUITINGOkayama, 700-8558, Japan
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Osaka Metropolitan University Hospital
RECRUITINGOsaka, 545-8586, Japan
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Pitie Salpetriere University Hospital
RECRUITINGParis, Île-de-France Region, 75013, France
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Sheba Medical Center
RECRUITINGRamat Gan, Central District, 5262100, Israel
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Swedish Medical Center
RECRUITINGSeattle, Washington, 98122, United States
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Szpital Specjalistyczny nr 1 w Bytomiu
RECRUITINGBytom, Silesian Voivodeship, 41-902, Poland
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USF Health
RECRUITINGTampa, Florida, 33612, United States
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UZ Leuven
RECRUITINGLeuven, Vlaams-Brabant, 3000, Belgium
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Uniklinikum Salzburg
RECRUITINGSalzburg, 5020, Austria
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Universitaetsklinikum Erlangen
RECRUITINGErlangen, 91054, Germany
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Universitaetsklinikum Koeln
RECRUITINGCologne, 50937, Germany
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Universitaetsklinikum Magdeburg
RECRUITINGMagdeburg, Saxony-Anhalt, 39120, Germany
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University College London Hospital
RECRUITINGLondon, London, City of, NW1 2PG, United Kingdom
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University of Colorado Anschutz Medical Campus
RECRUITINGAurora, Colorado, 80045, United States
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University of Miami Hospital and Clinics, Sylvester Cancer Center
RECRUITINGMiami, Florida, 33136, United States
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Universitätsklinikum Leipzig
RECRUITINGLeipzig, Saxony, 04103, Germany
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Vancouver General Hospital
RECRUITINGVancouver, British Columbia, V5Z 1M9, Canada
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Weill Cornell Medical College
RECRUITINGNew York, New York, 10065, United States
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Yokohama City University Hospital
RECRUITINGYokohama, Kanagawa, 236-0004, Japan
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Conditions
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