New hope for stubborn lupus: drug targets fever and inflammation

NCT ID NCT07381465

First seen Feb 02, 2026 · Last updated May 13, 2026 · Updated 9 times

Summary

This small pilot study tests a drug called firsekibart in 15 adults with mild-to-moderate lupus who did not get better with usual therapies. The drug blocks a protein (IL-1) that causes fever and inflammation. The main goal is to see if lupus symptoms improve after 12 weeks of treatment.

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