LOWER URINARY TRACT SYMPTOMS

This trial tests whether injecting a fluid mixture around the prostate before surgery can make the procedure easier and reduce bleeding. Men with enlarged prostates and moderate-to-severe urinary symptoms will be randomly assigned to either the new hydrodissection-assisted techni…

This study tests whether changing the environment—by playing relaxing music or dimming the lights—can lower anxiety in adults undergoing a urodynamic study, a test that measures how well the bladder stores and releases urine. About 220 participants with ongoing bladder symptoms w…

This study compares two common drugs, silodosin and tamsulosin, to see which one better relieves moderate to severe urinary symptoms caused by an enlarged prostate. About 140 men aged 50 and older will take each medication for four weeks in a crossover design, with no washout per…

This study tests a gel called PuraStat that is applied inside the prostate after a water-jet surgery (Aquablation) for enlarged prostate. The goal is to see if it reduces bleeding enough for men to go home the same day. Twenty-five men will take part in this early pilot study.

This study compares taking tamsulosin every day versus every other day in 288 men aged 40 and older with enlarged prostate and moderate-to-severe urinary symptoms. The goal is to see if the every-other-day schedule controls symptoms just as well while possibly causing fewer sexua…

This study will follow 500 Beijing residents aged 60 and older to see how urinary function (like bladder and kidney health) relates to the development of multiple chronic conditions such as diabetes, heart disease, and Alzheimer's. Participants will have regular health checks, bl…

This study will follow 200 women who are either taking GLP-1 weight loss drugs or undergoing bariatric surgery. Researchers want to see how these treatments change pelvic floor symptoms like incontinence and prolapse. Participants do not need to have any pelvic floor symptoms to …