LIVER DISEASES

This study tests a new treatment called QEL-001, made from a patient's own cells, to help their body accept a donated liver without needing lifelong anti-rejection drugs. About 33 adults who received a liver transplant 1 to 5 years ago will receive the therapy and then try to sto…

This study tests a stepped alcohol treatment program delivered by phone or video for 180 adults with chronic liver disease who drink too much. Participants are randomly assigned to either the program or usual care. The goal is to see if the program helps reduce drinking and impro…

This study looks at how things like income, education, and social support affect the health of children who get a liver transplant. Researchers will survey 500 families and interview some in depth to understand the challenges they face. The goal is to find ways to help all childr…

This study tests whether a personalized, behavior-based program can help people with early signs of liver disease (fatty liver or scarring) manage their condition better than standard care. About 49 adults with risk factors like obesity or diabetes will take part. The goal is to …

This study followed children and young adults with genetic liver diseases that cause bile buildup (cholestasis), including Alagille syndrome and alpha-1 antitrypsin deficiency. Researchers tracked disease progression, such as need for liver transplant or growth problems, to bette…

This study looks at how bariatric surgery affects the way the body handles sugar and fat. Researchers will collect tissue and blood samples from 500 people having weight-loss surgery or other procedures. The goal is to learn more about how the intestines signal other organs, whic…

This study planned to test a technique that uses heat to seal the needle track after a liver, kidney, or spleen biopsy, aiming to reduce bleeding in patients at high risk. It was withdrawn before enrolling any participants. The goal was to see how well patients and doctors tolera…

This study follows 300 patients with severe alcoholic hepatitis who receive an early liver transplant (before 6 months of sobriety). Researchers track survival and alcohol relapse for one year after surgery, and also survey public opinion about this practice. The goal is to bette…