LEPTOMENINGEAL METASTASES
Clinical trials for LEPTOMENINGEAL METASTASES explained in plain language.
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New hope for deadly breast cancer spread: drug duo targets brain lining
Disease control Recruiting nowThis study tests a combination of two drugs—sacituzumab govitecan (given through a vein) and pemetrexed (given into the spinal fluid)—for people with HER2-negative breast cancer that has spread to the lining of the brain and spinal cord (leptomeningeal metastases). The goal is to…
Matched conditions: LEPTOMENINGEAL METASTASES
Phase: PHASE1, PHASE2 • Sponsor: Guangzhou Medical University • Aim: Disease control
Last updated May 17, 2026 10:43 UTC
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Could an old drug offer new hope for brain metastases?
Disease control Recruiting nowThis early-phase study tests whether deferoxamine, given directly into the fluid around the brain and spinal cord, is safe for people with leptomeningeal metastases (cancer spread to the lining of the brain). About 35 adults with solid tumor cancers will receive different doses t…
Matched conditions: LEPTOMENINGEAL METASTASES
Phase: PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 17, 2026 10:37 UTC