LEPTOMENINGEAL METASTASES
Clinical trials for LEPTOMENINGEAL METASTASES explained in plain language.
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New combo therapy tackles rare brain cancer spread
Disease control CompletedThis early-phase trial tested the drug avelumab (Bavencio) combined with whole-brain radiotherapy in 16 patients with leptomeningeal disease, a condition where cancer spreads to the lining of the brain and spinal cord. The main goal was to find a safe dose and check for side effe…
Matched conditions: LEPTOMENINGEAL METASTASES
Phase: PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Proton vs. photon: which radiation works better for leptomeningeal metastases?
Disease control CompletedThis study compares two radiation approaches for leptomeningeal metastases, a condition where cancer spreads to the fluid and lining around the brain and spinal cord. One group receives proton craniospinal irradiation, which targets the entire brain and spine, while the other get…
Matched conditions: LEPTOMENINGEAL METASTASES
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Spinal fluid clues could help detect breast cancer spread to the brain
Knowledge-focused CompletedThis study looked at spinal fluid from 51 breast cancer patients whose cancer may have spread to the lining of the brain and spinal cord (leptomeningeal metastases). Researchers compared a new blood test technique (CellSearch) with standard spinal fluid analysis to see which bett…
Matched conditions: LEPTOMENINGEAL METASTASES
Phase: NA • Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC