New hope for deadly breast cancer spread: drug duo targets brain lining
NCT ID NCT06462092
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 30 times
Summary
This study tests a combination of two drugs—sacituzumab govitecan (given through a vein) and pemetrexed (given into the spinal fluid)—for people with HER2-negative breast cancer that has spread to the lining of the brain and spinal cord (leptomeningeal metastases). The goal is to find a safe dose and see if it helps control the disease. About 34 adults will take part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The Affiliated Huizhou Hospital, Guangzhou Medical University
RECRUITINGHuizhou, Guangdong, 516000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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