JUVENILE MYELOMONOCYTIC LEUKEMIA
Clinical trials for JUVENILE MYELOMONOCYTIC LEUKEMIA explained in plain language.
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New drug combo aims to make stem cell transplants safer for blood cancer patients
Disease control Recruiting nowThis Phase 2 trial is testing a stem cell transplant from a donor for people with various blood cancers and bone marrow disorders. The transplant uses strong chemotherapy or radiation to wipe out the diseased marrow, then replaces it with healthy donor cells. A new combination of…
Matched conditions: JUVENILE MYELOMONOCYTIC LEUKEMIA
Phase: PHASE2 • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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Immune cell booster trial offers hope for blood cancer relapse after transplant
Disease control Recruiting nowThis early-stage trial tests a special type of immune cell (CIML NK cells) combined with a low dose of IL-2 in people whose blood cancer (like AML or MDS) came back after a stem cell transplant. The goal is to find a safe dose and see if it can put the cancer back into remission.…
Matched conditions: JUVENILE MYELOMONOCYTIC LEUKEMIA
Phase: PHASE1 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New transplant method aims to cut dangerous side effects in blood cancer patients
Disease control Recruiting nowThis study tests a stem cell transplant method that removes certain immune cells (T-cells and B-cells) from the donor cells. The goal is to reduce graft-versus-host disease, a serious complication where donor cells attack the patient's body. The trial includes 20 children and you…
Matched conditions: JUVENILE MYELOMONOCYTIC LEUKEMIA
Phase: PHASE2 • Sponsor: University of Florida • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Supercharged immune cells take on relapsed leukemia
Disease control Recruiting nowThis early-phase trial tests a new immunotherapy for children and adults with acute leukemia that has come back or not responded after a donor stem cell transplant. The treatment uses specially engineered donor T cells designed to recognize and attack a protein called HA-1 found …
Matched conditions: JUVENILE MYELOMONOCYTIC LEUKEMIA
Phase: PHASE1 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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New stem cell transplant aims to cut dangerous side effects in blood cancer patients
Disease control Recruiting nowThis study tests a special stem cell transplant for children and adults with blood cancers like leukemia. The transplant uses stem cells that have had certain immune cells removed to lower the risk of graft-versus-host disease, a serious complication. About 70 participants will r…
Matched conditions: JUVENILE MYELOMONOCYTIC LEUKEMIA
Phase: PHASE2 • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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New stem cell transplant method shows promise for kids with tough blood cancers
Disease control Recruiting nowThis study tests a new way to do stem cell transplants for children with blood cancers like leukemia. It uses a half-matched family donor and removes certain immune cells from the donated cells to lower risks. The goal is to see if this method is safe and helps the child's body a…
Matched conditions: JUVENILE MYELOMONOCYTIC LEUKEMIA
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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New cell addback could shield kids from deadly infections after transplant
Disease control Recruiting nowThis study tests whether giving children with leukemia a special type of donor immune cell (CD45RA-depleted) after a stem cell transplant can help their immune system recover faster and lower the risk of serious viral or fungal infections. The trial enrolls 50 children under 25 w…
Matched conditions: JUVENILE MYELOMONOCYTIC LEUKEMIA
Phase: NA • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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New cell therapy aims to supercharge immune recovery in young cancer patients
Disease control Recruiting nowThis early-phase study tests whether a special cell therapy called T-allo10 can safely help rebuild the immune system in children and young adults (up to age 45) with blood cancers who have received a stem cell transplant. The treatment is given after the transplant to speed up r…
Matched conditions: JUVENILE MYELOMONOCYTIC LEUKEMIA
Phase: PHASE1 • Sponsor: Porteus, Matthew, MD • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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New screening trial aims to match kids with relapsed leukemia to targeted therapies
Knowledge-focused Recruiting nowThis study screens children and young adults up to age 22 whose leukemia has returned or is hard to treat. By testing their blood and bone marrow, doctors can identify specific genetic markers to match them with the most promising experimental treatments. The goal is to build a r…
Matched conditions: JUVENILE MYELOMONOCYTIC LEUKEMIA
Phase: PHASE1, PHASE2 • Sponsor: PedAL BCU, LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Scientists launch effort to crack the code of rare childhood blood cancers
Knowledge-focused Recruiting nowThis study is collecting information from 260 children and teens with rare blood cancers called myelodysplastic syndromes (MDS) and juvenile myelomonocytic leukemia (JMML). Researchers are using advanced genetic tests to improve how these diseases are diagnosed and classified. Th…
Matched conditions: JUVENILE MYELOMONOCYTIC LEUKEMIA
Sponsor: University Hospital Freiburg • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Scientists hunt for smarter treatments for kids with leukemia
Knowledge-focused Recruiting nowThis study is collecting genetic and drug sensitivity data from 300 children with leukemia to better understand why some cases relapse and how to target them more precisely. Researchers will analyze tumor DNA, gene activity, and test drugs on patient cells in the lab. The goal is…
Matched conditions: JUVENILE MYELOMONOCYTIC LEUKEMIA
Sponsor: Chinese University of Hong Kong • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC