INTERSTITIAL LUNG DISEASE

This small study will test a drug called emapalumab in 5 adults with a rare, rapidly worsening lung disease linked to dermatomyositis. The drug is already used for a similar immune overreaction condition. Researchers will check if it improves oxygen needs, lung function, and CT s…

This phase 3 study tests the long-term safety of an inhaled drug called treprostinil palmitil for people with pulmonary hypertension caused by interstitial lung disease. About 344 adults who completed an earlier trial will take the drug for up to 2 years. Researchers will track s…

This early-stage trial will test whether injecting stem cells from donated umbilical cords into the lungs is safe for people with interstitial lung disease (ILD). Twenty-four adults with ILD will receive different doses through a bronchoscope. The main goal is to find the safest …

This study tests whether a combination of three drugs (prednisone, azithromycin, and hydroxychloroquine) can slow lung function decline in adults with interstitial lung disease caused by certain gene variants. About 30 participants will receive either the triple therapy or standa…

This study tests a new radioactive tracer called 18F-FAPI-74 that may help detect scar tissue (fibrosis) in the heart and lungs earlier than current methods. Researchers will compare this new PET/CT scan to standard imaging in 210 adults with conditions like lung disease or heart…

This study will test a handheld ultrasonic spirometer against a conventional hospital spirometer in 100 adults with chronic respiratory diseases like COPD or asthma. Each participant will use both devices to see if the portable one gives accurate and reliable results. If successf…

This study tests a special PET probe that targets a protein called DDR2, which is linked to lung scarring in interstitial lung disease. Researchers will scan 50 patients to see if the probe can accurately detect the disease and also check for related cognitive problems. The goal …

This study tests whether a 16-week home exercise program can improve daily function in 30 adults with pulmonary hypertension linked to interstitial lung disease. Participants will receive daily texts or emails with aerobic and strength exercises. Researchers will measure changes …

This study tests whether playing video games that involve breathing exercises can improve lung function and exercise capacity in people with interstitial lung disease. 42 participants will be split into two groups: one doing standard rehab, the other adding video game-based exerc…

This study tests a lightweight, battery-powered device called MoblO2 that automatically adjusts oxygen flow to keep blood oxygen at a healthy level during exercise. It is designed for people with COPD or interstitial lung disease who need supplemental oxygen. Over two weeks, 48 p…

This study tests whether a new type of home oxygen therapy, called high-flow nasal cannula (HFNC), can improve breathing comfort and quality of life for people with long-term lung or heart conditions. Participants will try both HFNC and standard oxygen therapy for two weeks each …

This study will track 427 adults with interstitial lung disease (ILD) who need a bronchoscopy as part of their care. Researchers want to see how often complications happen within 30 days after the procedure. The goal is to better understand the risks so doctors can make safer cho…

This study tests whether giving people with heart or lung conditions real-time air pollution data helps them exercise outdoors more safely. 80 participants will use a smartphone platform that tracks their walking and local air quality. The goal is to see if this approach reduces …

This study will create and test a WeChat mini-program that provides health education to people with interstitial lung disease. The program covers disease knowledge, medication, diet, and rehabilitation, and allows patients to check test results and consult with doctors. Researche…