IMMUNOSUPPRESSION

This study aims to see if a special ultrasound scan (FibroScan) can help doctors safely reduce the amount of strong anti-rejection drugs that liver transplant patients must take for life. These drugs prevent organ rejection but can cause serious long-term side effects like kidney…

This study is testing whether a drug called infliximab works better alone or when combined with other immunosuppressive medications to control Crohn's disease in children. It will involve 128 children aged 6-18 who have active Crohn's disease. The main goal is to see which approa…

This study is testing whether checking a patient's genes before a kidney transplant can help doctors prescribe the correct starting dose of a crucial anti-rejection drug called tacrolimus. It will compare this genetic-guided approach to the current standard of care to see if it g…

This study is testing if taking all anti-rejection drugs once a day is as safe and effective as taking them twice a day for people who have received a liver transplant. The goal is to make the lifelong medication routine easier to follow, which could help patients stick to their …

This is the first-ever study to test transplanting a whole bladder from a deceased donor into a patient with end-stage bladder disease. The goal is to see if this robotic surgery is a feasible and better-tolerated alternative to current major surgeries that use a piece of bowel. …

This study aims to understand how genetic immune system problems affect oral health, particularly gum disease. Researchers will compare people with immune disorders, those with severe gum disease, and healthy volunteers by collecting samples like saliva, plaque, and blood. The go…

This study aims to understand what happens to the immune system after severe injuries like car crashes or falls. Researchers will collect blood and bone marrow samples from 255 trauma patients and compare them to people having routine hip surgery. They want to learn why some inju…