IGA VASCULITIS

This study tests an oral drug called sparsentan in 67 children with certain kidney diseases that cause protein in the urine. The goal is to see if the drug safely reduces protein leakage and helps control the disease over about two years. Participants take the drug once daily, an…

This study compares three standard treatments for people with isolated skin vasculitis, a condition where blood vessels in the skin become inflamed. Researchers want to see which treatment works best to control symptoms and improve quality of life. About 90 adults with this condi…

This study tests a drug called ravulizumab in children aged 2 to 18 with a kidney disease called IgA nephropathy. The goal is to see if the drug can reduce protein in the urine, which is a sign of kidney damage. Participants receive the drug through an IV and are monitored for sa…

This study looks at skin samples from 50 people with different types of vasculitis, a condition where blood vessels become inflamed. Researchers want to understand how the disease affects skin tissue at a molecular level. Participants must have an active skin lesion and a confirm…

This study follows women with vasculitis (inflammation of blood vessels) who become pregnant. Researchers use online surveys to track disease activity and pregnancy outcomes across each trimester. The goal is to better understand how vasculitis affects pregnancy and what unique c…

This study collects tissue samples from 1,000 people with various forms of vasculitis (blood vessel inflammation). Researchers will analyze the samples along with medical data to find genes linked to the disease and spark new ideas for diagnosis and treatment. Participants must a…