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New hope for kids with kidney disease: drug trial targets protein leak

NCT ID NCT07024563

Recruiting now Disease control Sponsor: Alexion Pharmaceuticals, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 4 times

Summary

This study tests a drug called ravulizumab in children aged 2 to 18 with a kidney disease called IgA nephropathy. The goal is to see if the drug can reduce protein in the urine, a sign of kidney damage. Participants will receive the drug through an IV and be monitored for safety and effectiveness over about 2 years.

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Conditions

The condition(s) this trial relates to.

IgA glomerulonephritis IgA nephropathy, susceptibility to, 1 immunoglobulin A vasculitis proteinuria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HENOCH-SCHONLEIN PURPURA NEPHRITIS IGA VASCULITIS IGAN IGAVN IMMUNOGLOBULIN A NEPHROPATHY IMMUNOGLOBULIN A VASCULITIS ASSOCIATED NEPHRITIS

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Research Site

    NOT_YET_RECRUITING

    Palo Alto, California, 94304, United States

  • Research Site

    RECRUITING

    Aurora, Colorado, 80045, United States

  • Research Site

    RECRUITING

    Beijing, 100045, China

  • Research Site

    RECRUITING

    Shanghai, 201102, China

  • Research Site

    RECRUITING

    Genova, 16147, Italy

  • Research Site

    RECRUITING

    Roma, 00165, Italy

  • Research Site

    RECRUITING

    Torino, 10126, Italy

  • Research Site

    RECRUITING

    Wakayama, 641-8510, Japan

  • Research Site

    RECRUITING

    Seoul, 03080, South Korea

  • Research Site

    NOT_YET_RECRUITING

    Almería, 04009, Spain

  • Research Site

    RECRUITING

    Barcelona, 08035, Spain

  • Research Site

    RECRUITING

    Barcelona, 8950, Spain

  • Research Site

    RECRUITING

    Seville, 41013, Spain

  • Research Site

    RECRUITING

    Taipei, 10002, Taiwan

  • Research Site

    RECRUITING

    Taoyuan, 333, Taiwan

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