Which drug tames skin vasculitis best? new trial aims to find out

NCT ID NCT02939573

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests three standard medications—colchicine, dapsone, and azathioprine—in 90 people with isolated skin vasculitis (inflammation of small or medium blood vessels in the skin). Participants are randomly assigned to one of the drugs, and doctors track how well the skin responds over 12 months. The goal is to see which drug works best to control the condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

colchicine, dapsone, or azathioprine

What this could lead to

If successful, this trial could identify which of these three existing drugs works best for controlling skin vasculitis, helping doctors choose the most effective treatment.

What could go wrong

This is a phase 2 trial with only 90 participants, so results may not apply to everyone. The drugs have known side effects, and the study may not find a clear winner.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cutaneous leukocytoclastic angiitis cutaneous polyarteritis nodosa cutaneous vasculitis immunoglobulin A vasculitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Boston University School of Medicine

    COMPLETED

    Boston, Massachusetts, 02118, United States

  • Cleveland Clinic

    COMPLETED

    Cleveland, Ohio, United States

  • Hospital for Special Surgery

    COMPLETED

    New York, New York, 10021, United States

  • Mayo Clinic

    COMPLETED

    Rochester, Minnesota, 55905, United States

  • McGill University Health Centre

    RECRUITING

    Montreal, Quebec, H4A 3J1, Canada

    Contact Email: •••••@•••••

  • Northwell Health

    COMPLETED

    Lake Success, New York, 11042, United States

  • Penn State Hershey Medical Center

    COMPLETED

    Hershey, Pennsylvania, 17033, United States

  • St. Joseph's Healthcare

    RECRUITING

    Hamilton, Ontario, Canada

    Contact Email: •••••@•••••

  • Tohoku Medical and Pharmaceutical University Hospital

    COMPLETED

    Kyoto, 602-8566, Japan

  • UT Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact Email: •••••@•••••

  • University of Kansas Medical Center

    RECRUITING

    Kansas City, Kansas, United States

    Contact Email: •••••@•••••

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Email: •••••@•••••

  • University of Toronto Mount Sinai Hospital

    RECRUITING

    Toronto, Ontario, Canada

    Contact Email: •••••@•••••

  • University of Utah

    COMPLETED

    Salt Lake City, Utah, United States

  • University of Virginia

    RECRUITING

    Charlottesville, Virginia, 22903, United States

    Contact Email: •••••@•••••

  • Vanderbilt University

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact Email: •••••@•••••