HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Clinical trials for HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA explained in plain language.
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New weapon tested against Virus-Driven cancer
Disease control CompletedThis first-in-human study tested a new drug called CUE-101, designed to activate the immune system to fight cancers caused by HPV. It was given to about 80 adults with advanced head and neck cancer, either alone for patients who had already tried other treatments, or combined wit…
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: Cue Biopharma • Aim: Disease control
Last updated Apr 02, 2026 02:40 UTC
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New combo therapy aims to supercharge immune system against HPV cancer
Disease control CompletedThis study tested whether adding a new immunotherapy called PDS0101 to an existing drug (pembrolizumab) could better treat advanced head and neck cancer caused by HPV16. It involved 95 adults whose cancer had returned or spread. The goal was to see if the combination could help t…
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: PDS Biotechnology Corp. • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Spit test could spot throat cancer early
Diagnosis CompletedThis study tested a new oral rinse that looks for HPV DNA in saliva. Researchers wanted to see if the test could tell the difference between a common HPV infection and actual throat cancer. They compared results from 360 people—some with HPV-positive throat cancer and some withou…
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Sponsor: Dana-Farber Cancer Institute • Aim: Diagnosis
Last updated Mar 20, 2026 14:48 UTC
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Blood test could spot hidden cancer after surgery
Diagnosis CompletedThis study tested a new, highly sensitive blood test to find tiny amounts of leftover cancer after surgery in patients with HPV-related head and neck cancer. The goal was to see if detecting this 'molecular residual disease' could better predict which patients might have their ca…
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Diagnosis
Last updated Mar 11, 2026 14:53 UTC