HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Clinical trials for HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA explained in plain language.
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New hope for HPV+ head and neck cancer: experimental drug CUE-101 tested
Disease control CompletedThis early-phase study tested a new drug called CUE-101, alone or with pembrolizumab, in 80 adults with HPV16-positive head and neck cancer that had spread or returned. The main goals were to check safety and find the right dose. Researchers also looked at whether the drug helped…
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: Cue Biopharma • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Experimental combo targets HPV-Driven head and neck tumors
Disease control CompletedThis Phase 2 trial tested a combination of two immunotherapies—PDS0101 and pembrolizumab (Keytruda)—in 95 adults with HPV16-positive head and neck cancer that had returned or spread. The goal was to see if the combo could shrink tumors or slow the disease. Participants received b…
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: PDS Biotechnology Corp. • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Mouthwash test may spot hidden throat cancer
Diagnosis CompletedThis study tested a new mouthwash-based DNA test to see if it can find HPV in saliva, which might help detect HPV-related throat cancer early. Researchers compared results from 360 people — some with throat cancer and some without. The goal was to see how accurate the test is at …
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Sponsor: Dana-Farber Cancer Institute • Aim: Diagnosis
Last updated Jun 27, 2026 08:12 UTC
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Blood test spots hidden cancer after surgery in HPV head & neck patients
Diagnosis CompletedThis study tested a new blood test (liquid biopsy) to see if it could find any cancer left behind after surgery in 103 people with HPV-related head and neck cancer. The goal was to catch remaining disease early, which could help doctors decide if more treatment is needed. The tes…
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Diagnosis
Last updated Jun 27, 2026 08:00 UTC
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Math model may Fine-Tune radiation for throat cancer patients
Knowledge-focused CompletedThis study tested whether a mathematical model could help doctors choose the best radiation schedule for people with HPV-positive throat cancer. The goal was to see if personalized dosing could shrink tumors faster than standard treatment. Fifty-five adults took part, and researc…
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC