HEREDITARY ANGIOEDEMA TYPE I
Clinical trials for HEREDITARY ANGIOEDEMA TYPE I explained in plain language.
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Teens with rare swelling disorder get new drug tested
Disease control CompletedThis study looked at how a new oral medication (sebetralstat) works in the bodies of 11 teenagers aged 12 to 17 with hereditary angioedema (HAE) types I or II. The goal was to measure drug levels and timing in the blood. All participants were already in a larger HAE trial. The st…
Matched conditions: HEREDITARY ANGIOEDEMA TYPE I
Phase: PHASE3 • Sponsor: KalVista Pharmaceuticals, Ltd. • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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New pill shows promise for controlling rare swelling disorder
Disease control CompletedThis study looked at the long-term safety of an oral medication called KVD900 for treating swelling attacks in people with hereditary angioedema (HAE) types I or II. The trial enrolled 145 adolescents and adults who had already completed a previous study. Participants took KVD900…
Matched conditions: HEREDITARY ANGIOEDEMA TYPE I
Phase: PHASE3 • Sponsor: KalVista Pharmaceuticals, Ltd. • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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New drug navenibart aims to tame hereditary swelling attacks
Disease control CompletedThis early trial tested a new drug called navenibart in 29 people with hereditary angioedema (HAE), a condition that causes sudden, painful swelling attacks. Participants received one or two doses of the drug to check its safety and how well it might reduce attacks. The study is …
Matched conditions: HEREDITARY ANGIOEDEMA TYPE I
Phase: PHASE1, PHASE2 • Sponsor: Astria Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Real-world study shows lanadelumab keeps HAE attacks at bay for many patients
Disease control CompletedThis study followed 48 people with hereditary angioedema (HAE) in Poland who were taking lanadelumab as part of a national drug program. Researchers tracked how many participants remained attack-free over 24 months, how many attacks still needed rescue treatment, and the severity…
Matched conditions: HEREDITARY ANGIOEDEMA TYPE I
Sponsor: Takeda • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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New pill could stop swelling attacks in hereditary angioedema
Disease control CompletedThis study tested an oral medication called deucrictibant for quickly treating attacks of hereditary angioedema (HAE), a condition causing sudden, painful swelling. The trial involved 134 adolescents and adults with HAE types 1, 2, or 3. Participants took either the drug or a pla…
Matched conditions: HEREDITARY ANGIOEDEMA TYPE I
Phase: PHASE3 • Sponsor: Pharvaris Netherlands B.V. • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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New daily pill could stop painful swelling attacks in rare disease
Disease control CompletedThis study tested an oral drug called BCX4161 to prevent attacks of hereditary angioedema (HAE), a condition that causes sudden, painful swelling. Over 12 weeks, 110 adults with HAE took either a low dose, high dose, or placebo pill. Researchers tracked how many swelling attacks …
Matched conditions: HEREDITARY ANGIOEDEMA TYPE I
Phase: PHASE2, PHASE3 • Sponsor: BioCryst Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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New hope for kids with rare swelling disorder: sebetralstat shows promise
Symptom relief CompletedThis study tested a drug called sebetralstat in 36 children aged 2 to 11 with hereditary angioedema (HAE) types I or II, a condition that causes sudden, painful swelling. The goal was to see if the drug is safe and how well it works to relieve attacks. The trial was open-label, m…
Matched conditions: HEREDITARY ANGIOEDEMA TYPE I
Phase: PHASE3 • Sponsor: KalVista Pharmaceuticals, Ltd. • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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New pill could stop painful swelling attacks in rare disease
Symptom relief CompletedThis study tested an oral medication called deucrictibant for quickly relieving swelling and pain attacks in people with hereditary angioedema (HAE) types I and II. 74 adults received either one of three doses of the drug or a placebo during an attack. The main goal was to see if…
Matched conditions: HEREDITARY ANGIOEDEMA TYPE I
Phase: PHASE2 • Sponsor: Pharvaris Netherlands B.V. • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Real-World data on HAE attack treatment collected in completed study
Knowledge-focused CompletedThis study followed 88 people with hereditary angioedema (HAE) types I or II who already use icatibant for sudden attacks. Participants filled out diaries for 48 hours after each attack to report symptom changes, severity, and anxiety levels. The goal was to gather real-world inf…
Matched conditions: HEREDITARY ANGIOEDEMA TYPE I
Sponsor: KalVista Pharmaceuticals, Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC