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Teens with rare swelling disorder get new drug tested

NCT ID NCT05511922

Completed Disease control Sponsor: KalVista Pharmaceuticals, Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how a new oral medication (sebetralstat) works in the bodies of 11 teenagers aged 12 to 17 with hereditary angioedema (HAE) types I or II. The goal was to measure drug levels and timing in the blood. All participants were already in a larger HAE trial. The study is complete and helps guide dosing for younger patients.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hereditary angioedema hereditary angioedema type 1 hereditary angioedema type 2

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEREDITARY ANGIOEDEMA

Contacts and locations

Locations

  • KalVista Investgative Site

    Auckland, 1023, New Zealand

  • KalVista Investgative Site

    Frimley, GU16 7UJ, United Kingdom

  • KalVista Investigative Site

    Scottsdale, Arizona, 85251, United States

  • KalVista Investigative Site

    Little Rock, Arkansas, 72205, United States

  • KalVista Investigative Site

    San Diego, California, 92122, United States

  • KalVista Investigative Site

    San Diego, California, 92123, United States

  • KalVista Investigative Site

    Santa Monica, California, 90404, United States

  • KalVista Investigative Site

    Centennial, Colorado, 80112, United States

  • KalVista Investigative Site

    Colorado Springs, Colorado, 80907, United States

  • KalVista Investigative Site

    Evansville, Indiana, 47715, United States

  • KalVista Investigative Site

    Overland Park, Kansas, 66211, United States

  • KalVista Investigative Site

    Louisville, Kentucky, 40215, United States

  • KalVista Investigative Site

    Chevy Chase, Maryland, 20815, United States

  • KalVista Investigative Site

    Plymouth, Minnesota, 55446, United States

  • KalVista Investigative Site

    St Louis, Missouri, 63141, United States

  • KalVista Investigative Site

    Charlotte, North Carolina, 28277, United States

  • KalVista Investigative Site

    Cincinnati, Ohio, 45236, United States

  • KalVista Investigative Site

    Toledo, Ohio, 43617, United States

  • KalVista Investigative Site

    Dallas, Texas, 75231, United States

  • KalVista Investigative Site

    Layton, Utah, 84041, United States

  • KalVista Investigative Site

    Spokane, Washington, 99204, United States

  • KalVista Investigative Site

    Campbelltown, 2560, Australia

  • KalVista Investigative Site

    Vienna, 1090, Austria

  • KalVista Investigative Site

    Sofia, 1431, Bulgaria

  • KalVista Investigative Site

    Montreal, H2W 1R7, Canada

  • KalVista Investigative Site

    Grenoble, 38043, France

  • KalVista Investigative Site

    Lille, 59037, France

  • KalVista Investigative Site

    Paris, 75012, France

  • KalVista Investigative Site

    Berlin, 12203, Germany

  • KalVista Investigative Site

    Frankfurt, 60590, Germany

  • KalVista Investigative Site

    Mainz, 55131, Germany

  • KalVista Investigative Site

    Mörfelden-Walldorf, 64546, Germany

  • KalVista Investigative Site

    Athens, 11521, Greece

  • KalVista Investigative Site

    Athens, 11527, Greece

  • KalVista Investigative Site

    Haifa, 31048, Israel

  • KalVista Investigative Site

    Petach Tikvah, 4920235, Israel

  • KalVista Investigative Site

    Ramat Gan, 52621, Israel

  • KalVista Investigative Site

    Tel Aviv, 64239, Israel

  • KalVista Investigative Site

    Sapporo, Hokkaido, 002-8072, Japan

  • KalVista Investigative Site

    Chiba, 260-8677, Japan

  • KalVista Investigative Site

    Hiroshima, 730-8518, Japan

  • KalVista Investigative Site

    Kawagoe-shi, 350-8550, Japan

  • KalVista Investigative Site

    Maebashi, 371-8511, Japan

  • KalVista Investigative Site

    Soka-shi, 340-0041, Japan

  • KalVista Investigative Site

    Takatsuki-shi, 569-8686, Japan

  • KalVista Investigative Site

    Tokyo, 142-8666, Japan

  • KalVista Investigative Site

    Yokohama, 236-0004, Japan

  • KalVista Investigative Site

    Amsterdam, 1105 AZ, Netherlands

  • KalVista Investigative Site

    Sângeorgiu de Mureş, 547530, Romania

  • KalVista Investigative Site

    Martin, 036 59, Slovakia

  • KalVista Investigative Site

    Cape Town, 7700, South Africa

  • KalVista Investigative Site

    Barcelona, 08035, Spain

  • KalVista Investigative Site

    Barcelona, 08907, Spain

  • KalVista Investigative Site

    Madrid, 28046, Spain

  • KalVista Investigative Site

    Birmingham, B9 5SS, United Kingdom

  • KalVista Investigative Site

    Cambridge, CB2 0QQ, United Kingdom

  • KalVista Investigative Site

    Cardiff, CF14 4XW, United Kingdom

  • KalVista Investigative Site

    Leeds, LS9 7TF, United Kingdom

  • KalVista Investigative Site

    London, E1 2ES, United Kingdom

  • KalVista Investigative Site

    London, NW3 2QG, United Kingdom

  • Kalvista Investigative Site

    Hershey, Pennsylvania, 17033, United States