Promising HAE pill trial cut short by low enrollment

NCT ID NCT05055258

First seen May 16, 2026 ยท Last updated May 16, 2026

Summary

This study tested three doses of an experimental oral drug, KVD824, to see if it could prevent swelling attacks in people with hereditary angioedema (HAE) types I and II. The trial was stopped early because not enough volunteers enrolled, so results are limited. The drug works by blocking a protein involved in triggering attacks.

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Contacts and locations

Locations

  • KalVista Investigative Site

    Birmingham, Alabama, 35294, United States

  • KalVista Investigative Site

    Scottsdale, Arizona, 85251, United States

  • KalVista Investigative Site

    La Jolla, California, 92093, United States

  • KalVista Investigative Site

    Santa Monica, California, 90404, United States

  • KalVista Investigative Site

    Centennial, Colorado, 80112, United States

  • KalVista Investigative Site

    Tampa, Florida, 33620, United States

  • KalVista Investigative Site

    Chevy Chase, Maryland, 20815, United States

  • KalVista Investigative Site

    Boston, Massachusetts, 02114, United States

  • KalVista Investigative Site

    St Louis, Missouri, 63110, United States

  • KalVista Investigative Site

    Cincinnati, Ohio, 45231, United States

  • KalVista Investigative Site

    Hershey, Pennsylvania, 17033, United States

  • KalVista Investigative Site

    Dallas, Texas, 75390, United States

  • KalVista Investigative Site

    Spokane, Washington, 99204, United States

  • KalVista Investigative Site

    Campbelltown, New South Wales, Australia

  • KalVista Investigative Site

    Sofia, Bulgaria

  • KalVista Investigative Site

    North York, Ontario, Canada

  • KalVista Investigative Site

    Brno, Czechia

  • KalVista Investigative Site

    Prague, Czechia

  • KalVista Investigative Site

    Grenoble, France

  • KalVista Investigative Site

    Paris, France

  • KalVista Investigative Site

    Mainz, Rhineland-Palatinate, Germany

  • KalVista Investigative Site

    Berlin, Germany

  • KalVista Investigative Site

    Frankfurt am Main, Germany

  • KalVista Investigative Site

    Budapest, Hungary

  • KalVista Investigative Site

    Milan, Italy

  • KalVista Investigative Site

    Padova, Italy

  • KalVista Investigative Site

    Grafton, Auckland, New Zealand

  • KalVista Investigative Site

    Skopje, North Macedonia

  • KalVista Investigative Site

    San Juan, Puerto Rico

  • KalVista Investigative Site

    Birmingham, United Kingdom

  • KalVista Investigative Site

    Leeds, United Kingdom

  • KalVista Investigative Site

    London, United Kingdom

  • KalVista Investigative Site

    Newcastle upon Tyne, United Kingdom

Conditions

Explore the condition pages connected to this study.