New pill could stop swelling attacks in hereditary angioedema
NCT ID NCT06343779
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested an oral medication called deucrictibant for quickly treating attacks of hereditary angioedema (HAE), a condition causing sudden, painful swelling. The trial involved 134 adolescents and adults with HAE types 1, 2, or 3. Participants took either the drug or a placebo at the start of an attack to see if it shortened time to symptom relief. The goal is to offer a convenient, on-demand pill option for managing HAE attacks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
deucrictibant (oral soft capsule)
What this could lead to
If successful, this could provide a convenient, on-demand oral treatment to quickly relieve swelling attacks in people with hereditary angioedema.
What could go wrong
This is a completed Phase 3 trial, but results are not yet published. The drug may not prove significantly better than placebo, and side effects are possible. It is not a cure—patients would still need ongoing management.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEREDITARY ANGIOEDEMA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Study Site
Birmingham, Alabama, 35209, United States
-
Study Site
Paradise Valley, Arizona, 85258, United States
-
Study Site
Little Rock, Arkansas, 72205, United States
-
Study Site
San Diego, California, 92122, United States
-
Study Site
Santa Monica, California, 90404, United States
-
Study Site
Walnut Creek, California, 94598, United States
-
Study Site
Colorado Springs, Colorado, 80907-6231, United States
-
Study Site
Chevy Chase, Maryland, 20815, United States
-
Study Site
Boston, Massachusetts, 02115, United States
-
Study Site
Detroit, Michigan, 48202, United States
-
Study Site
St Louis, Missouri, 63141, United States
-
Study Site
Hershey, Pennsylvania, 17033, United States
-
Study Site
Dallas, Texas, 75231, United States
-
Study Site
Buenos Aires, B1629AHJ, Argentina
-
Study Site
Salta, 4400, Argentina
-
Study Site
Campbelltown, New South Wales, 2560, Australia
-
Study Site
Box Hill, 3128, Australia
-
Study Site
Graz, 8036, Austria
-
Study Site
Linz, 4021, Austria
-
Study Site
Vienna, 1090, Austria
-
Study Site
Paraná, 80810-100, Brazil
-
Study Site
Ribeirão Preto, 14048-900, Brazil
-
Study Site
Salvador, 41950-640, Brazil
-
Study Site
Santo André, 09060-870, Brazil
-
Study Site
São Paulo, 05403-000, Brazil
-
Study Site
Sofia, 1431, Bulgaria
-
Study Site
Sofia, 1680, Bulgaria
-
Study Site
Edmonton, Alberta, T6G 1Z1, Canada
-
Study Site
Bogotá, 00, Colombia
-
Study Site
Bogotá, 111221, Colombia
-
Study Site
Bogotá, 111711, Colombia
-
Study Site
Medellín, 050021, Colombia
-
Study Site
Brno, 602 00, Czechia
-
Study Site
Lille, 59037, France
-
Study Site
Paris, 75571, France
-
Study Site
Berlin, 12203, Germany
-
Study Site
Frankfurt am Main, 60590, Germany
-
Study Site
Frankfurt am Main, 60596, Germany
-
Study Site
Lübeck, 23538, Germany
-
Study Site
Hong Kong, Hong Kong
-
Study Site
Budapest, 1088, Hungary
-
Study Site
Dublin, D08 A978, Ireland
-
Study Site
Catania, 95124, Italy
-
Study Site
Milan, 20138, Italy
-
Study Site
Milan, 20097, Italy
-
Study Site
Padova, 35128, Italy
-
Study Site
Palermo, 90146, Italy
-
Study Site
Roma, 00133, Italy
-
Study Site
Chiba, 260-8677, Japan
-
Study Site
Hiroshima, 730-8518, Japan
-
Study Site
Kanagawa, 216-8511, Japan
-
Study Site
Osaka, 569-8686, Japan
-
Study Site
Tokyo, 113-8431, Japan
-
Study Site
Amsterdam, 1105 AZ, Netherlands
-
Study Site
Skopje, 1000, North Macedonia
-
Study Site
Krakow, 31-503, Poland
-
Study Site
San Juan, 00918, Puerto Rico
-
Study Site
San Juan, 00927, Puerto Rico
-
Study Site
Sângeorgiu de Mureş, 547530, Romania
-
Study Site
Riyadh, 11471, Saudi Arabia
-
Study Site
Singapore, 308433, Singapore
-
Study Site
Cape Town, 7700, South Africa
-
Study Site
Daegu, 41944, South Korea
-
Study Site
Seoul, 03080, South Korea
-
Study Site
Barcelona, 08035, Spain
-
Study Site
Barcelona, 08907, Spain
-
Study Site
Lund, 22185, Sweden
-
Study Site
Ankara, 06203, Turkey (Türkiye)
-
Study Site
Istanbul, 34093, Turkey (Türkiye)
-
Study Site
Izmir, 35100, Turkey (Türkiye)
-
Study Site
Bristol, BS10 5NB, United Kingdom
-
Study Site
Camberley, GU16 7UJ, United Kingdom
-
Study Site
Cambridge, CB2 0QQ, United Kingdom
-
Study Site
Leeds, LS9 7TF, United Kingdom
-
Study Site
London, E1 2ES, United Kingdom
-
Study Site
Plymouth, PL6 8DH, United Kingdom