HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSES
Clinical trials for HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSES explained in plain language.
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New hope for adults with HLH: gentler treatment combo under study
Disease control Recruiting nowThis phase 2 trial is testing a combination of ruxolitinib and a reduced-intensity version of the standard HLH-94 regimen (dexamethasone and etoposide) in 36 adults newly diagnosed with hemophagocytic lymphohistiocytosis (HLH), a rare condition where the immune system attacks the…
Matched conditions: HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSES
Phase: PHASE2 • Sponsor: Jerry Lee, MD, MSc, MPhil • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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New study sheds light on mysterious immune disease in adults
Knowledge-focused Recruiting nowThis study is following 81 adults with a rare condition called hemophagocytic lymphohistiocytosis (HLH), where the immune system becomes dangerously overactive. Researchers aim to better understand the disease's features and how patients respond to treatments like steroids and ch…
Matched conditions: HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSES
Sponsor: Samsung Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New HLH registry aims to unlock secrets of rare immune disease
Knowledge-focused Recruiting nowThis study is a registry that collects information from 200 people with hemophagocytic lymphohistiocytosis (HLH), a rare condition where the immune system becomes dangerously overactive. Researchers will track how quickly HLH is diagnosed, what treatments are used, and what compl…
Matched conditions: HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSES
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Large study aims to uncover best treatments for lymphoma patients with dangerous immune reaction
Knowledge-focused Recruiting nowThis study is observing 2,000 lymphoma patients who also develop hemophagocytic lymphohistiocytosis (HLH), a severe immune overreaction. Researchers will collect data on which treatments patients receive and how they respond, aiming to identify factors that improve survival at 18…
Matched conditions: HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSES
Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Massive registry launched to see if Blood-Filtering device helps sickest patients
Knowledge-focused Recruiting nowThis registry is tracking 3,000 critically ill patients who receive the CytoSorb blood-filtering device in real-world intensive care settings. The goal is to collect data on how the device is used and whether it relates to patient survival. It covers many conditions like sepsis, …
Matched conditions: HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSES
Sponsor: CytoSorbents, Inc • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:43 UTC
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New study aims to crack the code of autoimmune diseases
Knowledge-focused Recruiting nowThis study is collecting blood, urine, and stool samples from 500 children with autoimmune diseases and healthy controls. Researchers will analyze these samples to find molecular patterns that could help diagnose these conditions and guide treatment decisions. The goal is to crea…
Matched conditions: HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSES
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:28 UTC