HEMATOLOGIC NEOPLASMS

This study tests three different flu vaccines in 60 adults with blood cancers like leukemia or lymphoma, including those who had a stem cell transplant or CAR-T therapy. The goal is to see which vaccine triggers the strongest immune response. Results will help doctors choose the …

This study aims to see if a lower dose of the drug cyclophosphamide can prevent graft-versus-host disease (a common complication where donor cells attack the body) while causing fewer side effects in older or frail adults with blood cancers. Participants will receive a bone marro…

This study tests a new approach for people with high-risk blood cancers like leukemia and lymphoma. It combines a half-matched bone marrow transplant with specially engineered immune cells (CAR T-cells) to attack the cancer. The goal is to see if giving both treatments together i…

This study is for people with high-risk blood cancers like leukemia or lymphoma who are getting a stem cell transplant. Even after a transplant, the cancer can return. Researchers want to see if giving a small dose of the donor's white blood cells just one week after the transpla…

This study tests whether red blood cells stored with less oxygen (hypoxic RBCs) are safer and more effective than standard red blood cells for people with blood cancers who need regular transfusions. About 24 adults with transfusion-dependent blood cancers will receive both types…

This study tests whether a medicine called tranexamic acid (TXA) can safely replace routine platelet transfusions to prevent bleeding in adults receiving a stem cell transplant for blood cancer. About 662 participants will be randomly assigned to receive either TXA with platelet …

This study tests whether a mind-body group program can help reduce fatigue in people with blood cancers who have finished chemotherapy or radiation. About 94 adults will be randomly assigned to the program or usual care. The goal is to see if this supportive approach improves ene…

This study tests whether a computer brain-training program (Lumosity) can improve memory and thinking in people who have had a stem cell transplant for blood cancer. About 60 survivors, 3 to 6 months after transplant, will either use the program or wait. The goal is to see if the…

This study uses advanced genetic testing (next generation sequencing) to look for early warning signs of pre-myeloid cancers and bone marrow failure in 2000 people. Participants have certain blood abnormalities or genetic markers that may increase their risk. The goal is to bette…

This study looks at how cancer impacts not just the patient, but their entire family. Researchers will survey 240 Danish patients with breast, prostate, colorectal cancer, or lymphoma, along with their caregivers. The goal is to understand family health, needs, and emotional well…

This study enrolls up to 10,000 adults with cancer to see how often doctors follow recommendations from a special team called the Precision Medicine Molecular Tumor Board. The team reviews each patient's genetic test results to suggest personalized treatments. Researchers will tr…

This study collects blood, bone marrow, urine, and tissue samples from people with cancer or blood disorders, as well as from their healthy family members who are stem cell donors. The samples are used in lab research to better understand diseases, improve treatments, and find ne…