New bleeding prevention strategy tested in stem cell transplants
NCT ID NCT04448184
First seen Jan 10, 2026 · Last updated Apr 24, 2026 · Updated 14 times
Summary
This study tests whether a medicine called tranexamic acid (TXA) can safely replace routine platelet transfusions to prevent bleeding in adults receiving a stem cell transplant for blood cancer. About 662 participants will be randomly assigned to receive either TXA with platelet transfusions only if needed, or standard preventive platelet transfusions. The goal is to see which approach better reduces serious bleeding events.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Locations
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Cross Cancer Institute
RECRUITINGEdmonton, Alberta, Canada
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Dalhousie University
NOT_YET_RECRUITINGHalifax, Nova Scotia, Canada
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Eastern Regional Health Authority
RECRUITINGSt. John's, Newfoundland and Labrador, A1B 3V6, Canada
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Hamilton Health Sciences - Juravinski Hospital and Cancer Centre
RECRUITINGHamilton, Ontario, L8V 1C3, Canada
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Hopital Maisonneuve-Rosemont
NOT_YET_RECRUITINGMontreal, Quebec, Canada
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London Health Sciences Centre
RECRUITINGLondon, Ontario, N6A5W9, Canada
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Memorial University
NOT_YET_RECRUITINGSt. John's, Newfoundland and Labrador, Canada
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Niagara Health System
RECRUITINGSt. Catharines, Ontario, L2S 0A9, Canada
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Princess Margaret Cancer Centre
WITHDRAWNToronto, Ontario, M5G 2M9, Canada
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Saskatchewan Cancer Agency
RECRUITINGSaskatoon, Saskatchewan, Canada
Contact Email: •••••@•••••
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The Ottawa Hospital
RECRUITINGOttawa, Ontario, K1H8L6, Canada
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Tom Baker Cancer Centre
RECRUITINGCalgary, Alberta, T2N4N2, Canada
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Conditions
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