HEART VALVE DISEASES

This study is testing a small implant called the Carillon device for people with heart failure and a leaky mitral valve. The device is placed in a vein near the heart to help the valve close better. Researchers will compare 300 people who get the implant to those who have a simil…

This study aims to find out if a telehealth (remote) cardiac rehabilitation program works as well as the traditional in-person version. It will enroll over 500 adults with various heart conditions who are eligible for rehab. Researchers will compare how much participants improve …

This early study is testing a new device called the Topaz system, which aims to replace a leaky tricuspid heart valve without major open-heart surgery. It will enroll about 15 adult patients with severe valve leakage who are at high risk for traditional surgery. Doctors will asse…

This is an early study to test the safety and function of a new device called the DUO System. It is designed to repair a severely leaking tricuspid heart valve using a catheter, avoiding open-heart surgery. The study will enroll 15 patients who have symptoms despite medication to…

This study is testing whether offering routine heart ultrasound screenings to nursing home residents can help reduce emergency hospital visits for heart problems. Researchers will compare nursing homes that offer the screenings to those that provide usual care, following 1,050 re…

This study aims to improve early detection of heart valve disease and heart failure in older adults from diverse communities. Researchers will train non-expert staff at local clinics to perform quick heart ultrasound scans during routine check-ups. The goal is to find these condi…

This study is collecting information about how patients do long-term after receiving a TAVR heart valve replacement procedure. It will follow 10,000 patients from multiple countries to see how they fare over time. The goal is to understand real-world outcomes, complications, and …

This study aims to measure exactly how long a heart-protecting solution called Del Nido cardioplegia keeps the heart safe during open-heart surgery. Researchers will enroll 80 adults having elective valve or aortic surgery and take small, timed blood samples during and after thei…

This study is testing if a special heart scan measurement, taken before surgery, can predict which patients will have a hard time coming off the heart-lung machine during their operation. Researchers will follow 213 adults having planned heart surgery to see if this scan result i…