GRANULOMATOSIS WITH POLYANGIITIS
Clinical trials for GRANULOMATOSIS WITH POLYANGIITIS explained in plain language.
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Cheaper version of vasculitis drug works just as well, study finds
Disease control CompletedThis study looked at 201 Canadian patients with ANCA-associated vasculitis to see if a cheaper biosimilar version of rituximab works as well as the original drug. Researchers compared how well the drugs controlled the disease, side effects, and how long patients waited for approv…
Matched conditions: GRANULOMATOSIS WITH POLYANGIITIS
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Disease control
Last updated May 17, 2026 04:01 UTC
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Smart dosing of rituximab may prevent relapses in rare vasculitis
Disease control CompletedThis study tested whether giving the drug rituximab based on blood markers (ANCA and CD19 cells) works better than giving it on a fixed schedule to prevent relapses in people with ANCA-associated vasculitis. 166 adults who were already in remission took part. The goal was to see …
Matched conditions: GRANULOMATOSIS WITH POLYANGIITIS
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated May 17, 2026 03:58 UTC
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Should patients with rare vasculitis stay on Low-Dose steroids? trial seeks answer
Disease control CompletedThis study looked at 159 adults with granulomatosis with polyangiitis (GPA), a rare disease causing blood vessel inflammation. Participants were randomly assigned to either keep taking a low dose of prednisone (5 mg/day) or stop it completely for about six months. The goal was to…
Matched conditions: GRANULOMATOSIS WITH POLYANGIITIS
Phase: PHASE3 • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated May 17, 2026 03:55 UTC
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Could a low-dose alcoholism drug ease vasculitis symptoms?
Symptom relief CompletedThis study tested whether a very low dose of naltrexone, a drug normally used for alcoholism, can improve physical health and quality of life in people with vasculitis (a group of rare blood vessel diseases). Sixty adults with different types of vasculitis took either the low-dos…
Matched conditions: GRANULOMATOSIS WITH POLYANGIITIS
Phase: PHASE2 • Sponsor: University of Pennsylvania • Aim: Symptom relief
Last updated May 17, 2026 03:56 UTC
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Scientists probe immune cell secrets to improve vasculitis care
Knowledge-focused CompletedThis completed study looked at 93 people with a rare blood vessel inflammation disease called granulomatosis with polyangiitis (GPA). Researchers studied neutrophils, a type of immune cell, to understand why they become overactive and damage the body. The goal was to find new mar…
Matched conditions: GRANULOMATOSIS WITH POLYANGIITIS
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 17, 2026 03:54 UTC