Scientists probe immune cells to unlock vasculitis mysteries

NCT ID NCT01862068

Completed Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at how certain immune cells, called neutrophils, behave in people with granulomatosis with polyangiitis (GPA), a rare blood vessel inflammation disease. Researchers collected blood samples from 93 participants, including patients with GPA and other related conditions, as well as healthy volunteers. The goal was to find proteins that could help doctors better track disease activity and guide treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could lead to better ways to monitor disease activity and more targeted, better-tolerated treatments for vasculitis.
What could go wrong: This is an observational study, not a treatment trial. It aims to understand the disease, not test a new therapy, so direct patient benefits are not immediate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anti-neutrophil cytoplasmic antibody-associated vasculitis eosinophilic granulomatosis with polyangiitis granulomatosis with polyangiitis microscopic polyangiitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GRANULOMATOSIS WITH POLYANGIITIS

Contacts and locations

Locations

Cochin Hospital

Paris, 75014, France

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