GERD (GASTROESOPHAGEAL REFLUX DISEASE)
Clinical trials for GERD (GASTROESOPHAGEAL REFLUX DISEASE) explained in plain language.
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New GERD drug shows promise in major trial
Disease control OngoingThis study tests a new medication, linaprazan glurate, to see if it heals esophagus damage from acid reflux better than a standard drug. About 500 adults with erosive esophagitis will take either the new drug or lansoprazole daily for up to 8 weeks. Doctors will use cameras to ch…
Matched conditions: GERD (GASTROESOPHAGEAL REFLUX DISEASE)
Phase: PHASE3 • Sponsor: Cinclus Pharma Holding AB • Aim: Disease control
Last updated Aug 06, 2026 00:00 UTC
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Can a diet and lifestyle program replace acid reflux pills after achalasia surgery?
Disease control OngoingThis study tests whether a structured program of dietary changes, lifestyle adjustments, and nutrient correction can reduce reflux symptoms in patients who had POEM surgery for achalasia. Many patients develop GERD after POEM and rely on long-term acid-reducing medications. The t…
Matched conditions: GERD (GASTROESOPHAGEAL REFLUX DISEASE)
Phase: NA • Sponsor: Asian Institute of Gastroenterology, India • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New GERD drug aims to keep esophagus healed, but trial never started
Disease control TerminatedThis study was designed to see if a new drug called linaprazan glurate could keep the esophagus healed in people with GERD-related erosive esophagitis, compared to an existing drug (lansoprazole). Participants would have taken daily pills for up to 52 weeks and had regular camera…
Matched conditions: GERD (GASTROESOPHAGEAL REFLUX DISEASE)
Phase: PHASE3 • Sponsor: Cinclus Pharma Holding AB • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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Which ablation method do patients prefer for throat patches?
Symptom relief OngoingThis study looks at two ways to remove small throat patches (inlet patches) that can cause discomfort in people with GERD. About 72 participants will receive either argon plasma or radiofrequency ablation. The goal is to see which method patients find more comfortable and which w…
Matched conditions: GERD (GASTROESOPHAGEAL REFLUX DISEASE)
Phase: NA • Sponsor: Assaf-Harofeh Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC