GASTROINTESTINAL BLEEDING

This study compares a new drug, Zastaprazan, against standard proton pump inhibitors (PPIs) for preventing stomach bleeding in 5,000 adults who had a heart attack and are on blood thinners. The goal is to see if routine use of Zastaprazan reduces serious complications like death,…

This study tests a new way to treat marginal ulcers that can form after gastric bypass surgery. Instead of just taking standard acid-reducing medication, some participants will also receive a low-thermal argon plasma treatment during an endoscopy. The goal is to see if this plasm…

This study uses a small camera in a capsule that you swallow to find bleeding in the small bowel that other tests missed. About 1300 adults with suspected bleeding will take part. The goal is to see how often the camera finds the source of bleeding and helps guide treatment.

This study tests a wireless capsule called Hemopill that patients swallow to detect active bleeding in the upper digestive tract. Researchers will compare its accuracy to standard endoscopy in 193 people with signs of bleeding. If it works, the capsule could help doctors quickly …

This study looks at whether easy-to-measure vital signs like heart rate and blood pressure can help predict how well people with liver cirrhosis and stomach bleeding will recover. Researchers will track 150 patients and use special scores based on these vital signs. The goal is t…

This study looks at how doctors at Strasbourg University Hospital manage severe stomach or intestinal bleeding in patients taking blood thinners (DOACs). Researchers will review medical records of 250 adults to see how often a drug called prothrombin complex concentrate is used t…

This study is testing a new scoring system called CAGIB to predict the risk of death in the hospital for people with liver cirrhosis who have sudden gastrointestinal bleeding. Researchers will compare CAGIB with two older scoring systems (Child-Pugh and MELD) in 3,000 patients ac…