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New score could save lives by predicting bleeding deaths in cirrhosis patients

NCT ID NCT04662918

Recruiting now Knowledge-focused Sponsor: Xingshun Qi Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study is testing a new scoring system called CAGIB to predict the risk of death in the hospital for people with liver cirrhosis who have sudden gastrointestinal bleeding. Researchers will compare CAGIB with two older scoring systems (Child-Pugh and MELD) in 3,000 patients across multiple countries. The goal is to see which score best helps doctors quickly identify the sickest patients so they can act faster.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could give doctors a more accurate tool to predict which patients are at highest risk of dying in the hospital, helping them make faster treatment decisions.
What could go wrong
This is an observational study, not a treatment trial. The new score may not prove better than existing ones, and results may not apply to all patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver Gastrointestinal Hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GASTROINTESTINAL BLEEDING

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Air Force Hospital of Northern Theater Command

    RECRUITING

    Shenyang, Liaoning, China

    Contact Email: •••••@•••••

  • Azienda di Rilievo Nazionale ad Alta Specializzazione Civico-Di Cristina-Benfratelli

    RECRUITING

    Palermo, Palermo, Italy

    Contact Email: •••••@•••••

  • Beijing Youan Hospital, Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, China

    Contact Email: •••••@•••••

  • Bezmialem Vakif University

    RECRUITING

    Istanbul, Istanbul, Turkey (Türkiye)

    Contact Email: •••••@•••••

  • Cathay General Hospital, Fu-Jen Catholic University School of Medicine

    NOT_YET_RECRUITING

    Taibei, Taiwan, China

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Charité University Medical Center

    RECRUITING

    Berlin, State of Berlin, Germany

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Ernakulam Medical Center

    NOT_YET_RECRUITING

    Kochi, Kochi, India

    Contact Email: •••••@•••••

  • First Affiliated Hospital of Fujian Medical University

    RECRUITING

    Fuzhou, Fujian, China

    Contact Email: •••••@•••••

  • First Affiliated Hospital of Nanchang University

    RECRUITING

    Nanchang, Jiangxi, China

    Contact Email: •••••@•••••

  • General Hospital of Northern Theater Command

    RECRUITING

    Shenyang, Liaoning, China

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • National Autonomous University of Mexico

    RECRUITING

    Mexico City, Mexico City, Mexico

    Contact Email: •••••@•••••

  • Shandong Provincial Hospital

    RECRUITING

    Jinan, Shandong, China

    Contact Email: •••••@•••••

  • São Paulo State University (UNESP), Botucatu Medical School

    RECRUITING

    São Paulo, São Paulo, Brazil

    Contact Email: •••••@•••••

  • Tangdu Hospital, Fourth Military Medical University,

    RECRUITING

    Xi'an, Shaanxi, China

    Contact Email: •••••@•••••

  • The First Affiliated Hospital of Xi'an Jiao Tong University

    RECRUITING

    Xi'an, Shaanxi, China

    Contact Email: •••••@•••••

  • The First Hospital of China Medical University

    RECRUITING

    Shenyang, Liaoning, China

    Contact Email: •••••@•••••

  • The Second Affiliated Hospital of Xi'an Jiao Tong University

    RECRUITING

    Xi'an, Shaanxi, China

    Contact Email: •••••@•••••

  • The Seventh Medical Center of Chinese PLA General Hospital

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, China

    Contact Email: •••••@•••••

  • The Six People's Hospital of Dalian

    RECRUITING

    Dalian, Liaoning, China

    Contact Email: •••••@•••••

  • The Six People's Hospital of Shenyang

    RECRUITING

    Shenyang, Liaoning, China

    Contact Email: •••••@•••••

  • The Wright Center for Graduate Medical Education, 501 S. Washington Avenue

    NOT_YET_RECRUITING

    Scranton, Pennsylvania, 18503, United States

    Contact Email: •••••@•••••

  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, China

    Contact Email: •••••@•••••

  • Xi'an Central Hospital

    RECRUITING

    Xi'an, Shaanxi, China

    Contact Email: •••••@•••••

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